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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Ro stress hindered ginseng root growth and ginsenoside production, but increased certain hormones and affected gene regulation related to plant growth and stress responses.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Reduced AR gene methylation may cause early pubic hair growth in girls.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.