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The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.

Compound 4 is a promising treatment for hair loss with low toxicity.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.

High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.

Kelulut Honey can help regulate sex hormone receptors in rats with Polycystic Ovary Syndrome, similar to common medications.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

A natural steroid in the body may protect against eye damage in glaucoma.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Gut microbes significantly affect brain steroid levels.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.