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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Dutasteride is more efficient than finasteride, but individual results vary.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Extracts improve hair growth in alopecia.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.