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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.

Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.