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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Finasteride reduces movement issues in Parkinson's disease rats.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Rats had lasting erectile problems after stopping a certain medication.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Solanum nigrum may help treat hair loss.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Personalized treatments for hair loss are becoming more effective by using genetic information.