research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
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research Seasonal Patterns and Trends in Dermatoses in Poland
In Poland, people search more for certain skin conditions depending on the season, and despite more STD infections, searches for them have decreased, suggesting a need for better sexual education.
research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs
Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
research MicroRNA/mRNA Regulatory Networks in the Control of Skin Development and Regeneration
MicroRNAs are crucial for controlling skin development and healing by regulating genes.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Keratinocytes Maintain Compartmentalization Between Dermal Papilla and Fibroblasts in 3D Heterotypic Tri-Cultures
Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
research HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro
A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.
research Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research Somatic Stem Cell Heterogeneity: Diversity in the Blood, Skin, and Intestinal Stem Cell Compartments
Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
research Are Hair Follicle Stem Cells Promising Candidates for Wound Healing?
Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
research Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
research Use of Human Intra-Tissue Stem/Progenitor Cells and Induced Pluripotent Stem Cells for Hair Follicle Regeneration
Stem cells can help regenerate hair follicles.
research mTOR Signaling Promotes Stem Cell Activation via Counterbalancing BMP-Mediated Suppression During Hair Regeneration
mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
research Isolation of Epithelial Stem Cells from Dermis by a Three-Dimensional Culture System
Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
research Stem Cells and the Skin
Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
research Conditions Simulating Androgenetic Alopecia
Different hair loss types need accurate diagnosis for proper treatment.
research Male Androgenetic Alopecia Is Due to Hair Follicle Stem Cell Inactivation
Male hair loss is caused by inactive hair follicle stem cells.
research Stem Cells and Their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Keratinocytes and Adipose-Derived Mesenchymal Stem Cells: The Heir and the Spare to Regenerative Cellular Therapies for Difficult-to-Heal Skin Wounds
Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
research Age-Associated Inflammation Inhibits Epidermal Stem Cell Function
Aging causes skin stem cells to work less effectively.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT Signaling Axis
PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
research Adipose-Derived Stem/Stromal Cells in Regenerative Medicine
Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
research Cutaneous Wound Healing: Canine Allogeneic ASC Therapy
Using stem cells from fat tissue can significantly improve wound healing in dogs.
research Raising Hairs
Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.
research Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Defining the Transcriptional Signature of Esophageal-to-Skin Lineage Conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
research Flexible Fate Determination Ensures Robust Differentiation in the Skin Hair Follicle
Hair follicle stem cells can change their role to ensure proper hair development.