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This study reports that a combination of adult stem cell released molecules and microneedling may be an effective and safe treatment for alopecia, promoting hair regrowth in 12 patients.

In this review, researchers examined how needle gauge and length impact the viability of human stem cells during injections, emphasizing the balance between minimizing tissue trauma and preserving cell viability to optimize clinical protocols.

This study found that a new "bead-jet" printing system for mesenchymal stem cells in Matrigel beads improved skeletal muscle regeneration and skin healing in a high-density, sparse pattern.

This study found that exosomes and secretome derived from rat hair follicle stem cells show promising potential for wound healing and tissue repair, demonstrating significant wound closure and suggesting their broader applicability in regenerative medicine.

PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.

This study found that a novel nano-engineered platform, PCA, significantly promoted hair regeneration in an androgenetic alopecia mouse model by enhancing angiogenesis and hair follicle stem cell proliferation, showing promise for future hair regrowth treatments.

This study found that in mice, hyper-activated JAK-STAT1 signaling due to EGFR inhibitor treatment leads to scarring alopecia, but JAK1/2 inhibition can restore hair follicle immune privilege and promote new hair growth.

This study found that the deletion of soluble epoxide hydrolase (sEH) in mice altered the hair follicle cycle and increased hair growth through effects on hair follicle stem and matrix cells.

This study shows that macrophage-induced TNF signaling can activate hair follicle stem cells and promote new hair follicle formation after wounding by regulating AKT/β-catenin pathways.

This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.

This study demonstrates that the transcription factor DLX5 can promote hair follicle stem cell differentiation through regulating the c-MYC/miR-29c-3p/NSD1 axis.

Retinoic acids temporarily change skin stem cells to a slower cycle and more differentiated state.

This study identified 232 stable proteins in exosomes from human adipose-derived mesenchymal stem cells and suggested a signaling axis that might support future androgenetic alopecia treatments.

This study found that dietary serine levels influence hair follicle stem cells' ability to balance hair regeneration and wound repair, offering insights for potential interventions to accelerate wound healing.

This study found that the E6 gene, but not E7, was responsible for HPV8-induced expansion of keratinocyte stem cells in hair follicle junctional zones in mice.

This review examines the potential of adipose-derived stem cells in disease treatment and highlights the need for further research to clarify their effectiveness and safety.

This study found that conditioned media from dental pulp stem cells stimulated significantly faster hair growth in mice, suggesting potential as a treatment for alopecia.

This study found that using induced pluripotent stem cell-derived mesenchymal stem cells with acellular nerve allografts significantly improved axon regeneration and functional recovery in rats with sciatic nerve injuries, suggesting a promising approach for clinical nerve repair therapies.

The researchers reported that conditioned media from deer antler mesenchymal stem cells may enhance hair and skin regeneration by modulating cellular responses through secretory vesicles.

In this study, the researchers developed a new protocol using human-induced pluripotent stem cells to efficiently create skin hair follicle organoids, which may aid in optimizing hair follicle growth and exploring treatments for alopecia.

This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.

This review discusses the potential of small extracellular vesicles (sEVs) as next-generation therapeutics, noting their ability to overcome biological barriers and modulate cellular environments for various diseases.

This study found that thyroid hormones T3 and T4 enhance keratin 15 promoter activity and stimulate CD200 expression in epithelial stem cells from human scalp hair follicles, affecting their growth and differentiation.

Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.

Hair follicle stem cells can become neural cells using different methods, with varying efficiency.

This study found that in skin blister healing, hair follicle development is compromised as stem cells repair wounds at the expense of morphogenesis gene expression.

This review discusses how chronic inflammation can lead to persistent stem cell activation and DNA damage, ultimately promoting cancer development and metastasis, but reports no new results.

In this study, researchers found that disrupting desmoglein 3 signaling in a mouse model of pemphigus vulgaris activates normally quiescent hair follicle stem cells, compromising their multipotency but prompting a regenerative response that restores stem cell function and structures.

In this study, researchers explored how hair follicle neural crest stem cell-derived exosomes, particularly those carrying miR-214-3p, promote neurite outgrowth and aid peripheral nerve regeneration, supported by detailed in vitro and in vivo data on nerve repair and functional recovery in rat models.

This dataset supports a study suggesting that hair follicle neural crest stem cell-derived exosomes carrying miR-214-3p may promote neurite outgrowth and aid peripheral nerve regeneration in vitro and in vivo.