![881 Ionizing radiation triggers dedifferentiation of outer root sheath cells into stem cell-like progenitors for hair follicle regeneration](/images/research/90a415d9-23ce-492c-9b3d-c5fc38f2c705/small/4021.jpg)
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210-240 / 1000+ results![881 Ionizing radiation triggers dedifferentiation of outer root sheath cells into stem cell-like progenitors for hair follicle regeneration](/images/research/90a415d9-23ce-492c-9b3d-c5fc38f2c705/small/4021.jpg)
![Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways](/images/research/8153a2f6-cb56-4ad7-a5cb-2cd55d499229/small/15216.jpg)
research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
![892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line](/images/research/8ab69fe5-46d4-4966-b313-e2253796d6c3/small/15903.jpg)
research 892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line
Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
research Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells
Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
![Stem Cells behind the Barrier](/images/research/ca266cd2-f114-43d2-a1da-bc31fc558780/small/33661.jpg)
research Stem Cells behind the Barrier
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation
Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
research Repigmentation by combined narrow‑band ultraviolet B/adipose‑derived stem cell transplantation in the mouse model: Role of Nrf2/HO‑1‑mediated Ca2+ homeostasis
Combining narrow-band ultraviolet B light and stem cell transplantation helps repigmentation in vitiligo by maintaining calcium balance in mice.
![Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review](/images/research/d8afe2c4-ecf2-4742-9a35-ad04b0f46a57/small/13056.jpg)
research Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review
Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
![Cytoprotective role of human dental pulp stem cell-conditioned medium in chemotherapy-induced alopecia](/images/research/6fef318b-632b-4fb3-8b7e-5422939d19dd/small/35328.jpg)
research Cytoprotective role of human dental pulp stem cell-conditioned medium in chemotherapy-induced alopecia
Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.
![Minoxidil delivered via a stem cell membrane delivery controlled release system promotes hair growth in C57BL/6J mice](/images/research/2180bf28-d295-4dca-92d8-36394df190ca/small/25866.jpg)
research Minoxidil delivered via a stem cell membrane delivery controlled release system promotes hair growth in C57BL/6J mice
A new method using stem cell membranes to deliver Minoxidil improved hair growth in mice better than Minoxidil alone.
![Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions](/images/research/9483ec87-0153-4a35-a820-4dae95edc30f/small/23171.jpg)
research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions
Spermidine may help reduce hair loss and deserves further testing as a treatment.
![Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia](/images/research/576f7a23-c29b-42f1-b7d5-5d0a714a76ca/small/19841.jpg)
research Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
![Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells](/images/research/ae7a95a3-f466-4f8b-9387-ea33cfaf32ec/small/34077.jpg)
research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells
Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
![Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing](/images/research/0bacd0fd-7930-40db-b7bd-3d7528caadd0/small/34403.jpg)
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
![Biochemistry of epidermal stem cells](/images/research/1933df7c-30a6-4f88-af99-0f1daa2ed1e4/small/19798.jpg)
research Biochemistry of epidermal stem cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
![Calcium regulation of stem cells](/images/research/dcf31e62-b857-41e3-8a93-747f4ccc55e4/small/30037.jpg)
research Calcium regulation of stem cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
![Stem cells and aberrant signaling of molecular systems in skin aging](/images/research/30e6450f-9b50-4984-b3c5-d21284aa7582/small/19696.jpg)
research Stem cells and aberrant signaling of molecular systems in skin aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
![Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis](/images/research/838c4d09-f759-4c8d-a3d2-3f1b7d8354e2/small/13064.jpg)
research Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
![Hair follicular cell/organ culture in tissue engineering and regenerative medicine](/images/research/679df725-ac77-4ccf-8972-311def1a37c8/small/22679.jpg)
research Hair follicular cell/organ culture in tissue engineering and regenerative medicine
Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
research Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation
Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.
![Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway](/images/research/6fd69a7c-f838-4074-8959-3a9cb5127077/small/25799.jpg)
research Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway
Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
![Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies](/images/research/bd0e9c9f-b4f3-485a-ae0d-807b9f2cbf15/small/19872.jpg)
research Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
![A New Horizon in Facial Plastic Surgery: Skin Tissue-Engineering and Stem Cell Therapy—Reality or Dream?](/images/research/38dbb2ba-015d-4032-a0e9-5a0224f8b699/small/12833.jpg)
research A New Horizon in Facial Plastic Surgery: Skin Tissue-Engineering and Stem Cell Therapy—Reality or Dream?
Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
![Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression](/images/research/a836079a-56bd-4757-b934-4bca4625a38b/small/28929.jpg)
research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
![Stem cell therapy and hair loss: Present evidence and future perspectives](/images/research/fd6ca7a0-d161-41a2-9a09-2986b1263a0b/small/17786.jpg)
research Stem cell therapy and hair loss: Present evidence and future perspectives
Stem cell therapy shows promise for hair loss treatment, but more research is needed to confirm its effectiveness.
![Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell <scp>RNA</scp>‐sequencing](/images/research/10fe82d5-437a-47f0-834d-08a95e85afc6/small/35170.jpg)
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA ‐sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
![In vitro analyses of CD4-protein function in dedifferentiated keratinocyte cell lines](/images/research/976ca055-27ce-48f7-8882-3478da0c034b/small/27862.jpg)
research In vitro analyses of CD4-protein function in dedifferentiated keratinocyte cell lines
The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.
![Live imaging of stem cells: answering old questions and raising new ones](/images/research/a5cb8cf6-ca1a-4c4c-883d-90c08ebac736/small/19579.jpg)
research Live imaging of stem cells: answering old questions and raising new ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging
Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
![Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation](/images/research/d012d987-0678-4f3d-836e-701b20dd10b9/small/12678.jpg)
research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.