36 citations
,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
298 citations
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January 2014 in “BioMed Research International” Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.
50 citations
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March 2014 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
24 citations
,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
17 citations
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February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
11 citations
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January 2013 in “Methods in molecular biology” The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
211 citations
,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
106 citations
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December 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
23 citations
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February 2015 in “International Journal of Molecular Sciences” Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
17 citations
,
July 2016 in “Medicine and Pharmacy Reports” Animal models are crucial for learning about hair loss and finding treatments.
3 citations
,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
2 citations
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May 2017 in “InTech eBooks” Stem cells could improve hair growth and new treatments for baldness are being researched.
May 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
9 citations
,
January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
83 citations
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May 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
10 citations
,
December 2021 in “Frontiers in cell and developmental biology” The research identified genes that explain why some sheep have curly wool and others have straight wool.
5 citations
,
May 2020 in “Life science alliance” Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
480 citations
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August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
139 citations
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August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
12 citations
,
January 2021 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
February 2024 in “Frontiers in physiology” Hair follicle stem cells help skin heal and grow during stretching.
53 citations
,
April 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
12 citations
,
December 2014 in “Journal of Investigative Dermatology” Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
12 citations
,
May 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Activating TRPV3 channels stops hair growth by killing hair follicle cells.
2 citations
,
April 2021 in “Journal of Cosmetic Dermatology” Umbilical cord-derived media is safe and effective for hair growth.
1 citations
,
May 2018 in “Journal of Investigative Dermatology” PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
1 citations
,
January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
May 2021 in “Journal of Investigative Dermatology” Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.
20 citations
,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.