3 citations,
April 2011 in “Expert Review of Dermatology” Male hair loss is caused by inactive hair follicle stem cells.
2 citations,
April 2019 in “Journal of Investigative Dermatology” Gasdermin A3 causes hair follicle stem cells to activate too early, leading to hair loss.
January 2024 in “International wound journal” The analysis shows growing research on stem cells for wound healing, with the US and China leading, and suggests focusing on how stem cells help in wound healing.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” KLF4 is important for keeping hair follicle stem cells inactive.
June 2022 in “Pflügers Archiv - European Journal of Physiology” The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.
Limbal Mesenchymal Stem Cell Secretome might help heal eye injuries by reducing inflammation and promoting tissue repair.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
April 2018 in “Journal of Investigative Dermatology” The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
April 2017 in “Journal of dermatological science” Young mice's hair follicle stem cells are best for turning into heart muscle cells.
September 2016 in “Journal of dermatological science” Human induced pluripotent stem cells can be used to create cells that help grow hair.
April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
February 2023 in “International Journal of Molecular Sciences” Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
December 2022 in “Nature Communications” Bead-jet printing of stem cells improves muscle and hair regeneration.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.
144 citations,
September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
106 citations,
September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.
95 citations,
May 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
77 citations,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
59 citations,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
47 citations,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
44 citations,
September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
20 citations,
December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.
18 citations,
October 2014 in “In vitro cellular & developmental biology. Animal” Hair follicle stem cells can become neural cells using different methods, with varying efficiency.
16 citations,
March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
15 citations,
May 2019 in “PLOS ONE” Substances from dental stem cells might help treat hair loss.