Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses how circadian clocks may influence diverse physiological functions beyond their established role in daily timekeeping, but it reports no new experimental findings.

This study found that hyperproliferative stimuli dysregulated the balance of stem cell divisions in keratinocytes, suggesting potential treatment strategies for both benign and cancerous hyperproliferative diseases.

This review discusses how chronic inflammation can lead to persistent stem cell activation and DNA damage, ultimately promoting cancer development and metastasis, but reports no new results.

This study found that the ocular surface epithelium in mice contains distinct stem cell populations with unique cell division dynamics that change behaviorally in response to different levels of injury.

This study reported that distinct stem/progenitor populations in the ocular surface epithelium have different cell division frequencies and respond differently to injury, with specific spatial compartmentalization and migration behaviors.

This review concluded that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage and promoting cancer development and metastasis from stem cell origins.

This review concludes that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage that promotes cancer development and metastasis, by affecting normal stem cells, cancer stem cells, and cancer cells.

This review highlights that chronic inflammation leads to ongoing activation of stem cells, causing DNA damage accumulation, which can promote cancer development and metastasis.

In this review, researchers concluded that chronic inflammation perpetually activates stem cells, allowing DNA damage accumulation and potentially promoting cancer development and metastasis by converting stem cells into cancer cells.

This literature review reports that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage, and eventually promoting cancer development and metastasis even before stem cells become cancerous.

This review concludes that chronic inflammation can lead to persistent activation of stem cells, which may accumulate DNA damage and ultimately promote cancer, while also facilitating cancer metastasis.

This review concludes that chronic inflammation persistently activates stem cells, leading to DNA damage accumulation that can promote cancer development and metastasis, affecting both stem and cancer cells.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This study found that Wnt signaling regulates the symmetric division of adult neural stem cells, increasing their numbers during subependymal regeneration, stroke response, and colony formation.

This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

This research reexamined transcriptomic data to study stem and progenitor cell proliferation in psoriasis, finding that the number of committed progenitor cells increased eight-fold in psoriatic skin without altering stem cell numbers, potentially identifying new therapeutic targets.

The conclusion is that the dermal papilla is crucial for hair follicle regrowth, and hair follicles undergo significant structural changes in addition to cell division during regeneration.

This review discusses the mechanisms governing epidermal stem and progenitor cell differentiation, emphasizing the balance necessary for maintaining skin barrier function, and reports no new experimental findings.

This study found that mouse hair follicle stem cells use symmetric cell division for maintenance and fate determination, and identified Gata6 as a crucial factor for their differentiation.

This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.

One type of progenitor cell can maintain normal skin in mice.

This study identified significant gene expression differences in human basal cell carcinoma, including up-regulation of zinc finger encoding genes, which are not entirely reflected in current mouse models.

This study found that inducing miR-205 reduces actin contractility and stiffness in hair follicle stem cells and progenitors, stimulating hair regeneration in both young and old mice.

This study developed the iCOUNT tool, which provides insights into stem cell behavior by tracking cell division events and molecular consequences in human and mouse neural stem/progenitor cells.

This study reports that hair regeneration in live mice involves spatially regulated stem cell divisions and requires mesenchymal interactions, observed in real-time using a novel non-invasive imaging method.

This study concluded that label-retaining cells in mouse epidermis differ in their sensitivity to proliferative stimuli, influencing their division and potential transdifferentiation without consistently depleting their population.

This review evaluates methods to study stem cell division patterns, particularly in the mammary gland, and discusses genetic factors affecting division modalities and their implications for breast cancer, but reports no new results.

This study found that mammary resident macrophages regulate mammary epithelium cell division and development, with implications for maintaining mammary stem cell activity and homeostasis.

This dissertation reports that horizontal basal cells in the olfactory epithelium undergo symmetric divisions balanced by population asymmetry, which supports their renewal and differentiation during tissue homeostasis and regeneration.

Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.