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This review outlines the various fibroblast subsets in the skin dermis, their origins, and their influence on epidermal stem cell behavior, highlighting the role of the local dermal niche in stem cell plasticity.

This study using human and animal models found that adipose-derived stem cell exosomes promoted hair growth and counteracted dihydrotestosterone's inhibitory effects, suggesting potential therapeutic applications for androgenetic alopecia.

This article explores questions about dormant hematopoietic stem cells and suggests avenues for future research, but does not present new experimental results.

This review provides guidance on using two-photon microscopy for real-time and long-term visualization of stem cell activity in live mice skin, focusing on its application in researching skin and stem cell biology.

In this review, researchers highlight preclinical and clinical studies on stem cell-based therapies for hair loss, noting promising early findings but indicating that further robust clinical research is necessary to better understand their effectiveness, safety, and mechanisms.

This study reported that reprogramming keratinocytes from plucked hair provides an easy, non-invasive, and efficient method for generating pluripotent iPSCs without the need for medical professionals or operating rooms.

This review discusses advancements and challenges in laboratory-based tissue-expansion and transplantation techniques for facial wound healing, noting potential for stem cell therapies but highlighting the ongoing absence of skin features like hair follicles in cultured grafts.

This study used two-photon microscopy to reveal that the dermal papilla is crucial for hair follicle regeneration and cannot be replaced by neighboring cells, providing new insights into stem cell behavior.

This narrative review highlights the potential of autologous adipose mesenchymal stem cell-derived exosomes (AMSCs-Exos) in anti-skin aging, noting their superior biocompatibility and manufacturing advantages while stressing the need for standardized production protocols to overcome existing application challenges.

This review discusses current and potential approaches using stem cells for treating hypopigmentation disorders like vitiligo but does not present new clinical findings.

This study found that exosomes derived from dental pulp mesenchymal stem cells (DPSC-Exos) significantly promoted hair regrowth and follicle density in a mouse model of androgenetic alopecia, showing similar efficacy to minoxidil by activating pathways that improve follicular vascularization and dermal papilla cell function.

This study identifies a specific cell population, PDGFRα+/Sca1+/CD34+ mesenchymal cells, which play a crucial role in regenerating hair follicles by promoting the downgrowth phase of the hair cycle, offering insights into organ morphogenesis and stem cell niches essential for adult hair regeneration.

This review found that image-guided techniques in regenerative aesthetic procedures may enhance accuracy and patient outcomes compared to traditional methods, but more high-quality randomized trials are needed to establish standardized protocols.

This research concludes that adipose mesenchymal stem cells are uniquely evolved to manage skin inflammation in newborns and their released molecules are the safest and most effective for skin therapeutics.

This research found that Foxc1 is critical for maintaining quiescence in activated hair follicle stem cells and that the cancer cell-of-origin influences tumor heterogeneity in mouse skin squamous cell carcinoma.

This study suggests that over-expression of Sp2 may limit stem cell differentiation and contribute to tumorigenic cell growth in mice.

This study found that Lrig1-positive cells in mouse epidermis are a previously unidentified source of adult interfollicular epidermal stem cells, which can contribute to sebaceous gland and epidermal lineage formation.

In this study, researchers differentiated induced pluripotent stem cells into cells with dermal papilla-like properties, demonstrating their potential role in hair follicle bioengineering and drug testing for hair growth.

This article reviews recent research on adult epidermal stem cells, discussing their properties and potential for reprogramming into patient-specific therapies, and emphasizes the need for further development while minimizing cancer risk.

This review examines the diversity and role of stem cells in the adult dermis, noting a lack of precise understanding about their hierarchy and relationship to dermal fibroblast subpopulations, and reports no new results.

This study found that the phenotype of Hedgehog/Gli-driven skin tumors in mice depends on the cell of origin, tissue context, and level of oncogenic signaling.

This study found that absence of the vitamin D receptor in keratinocytes impairs canonical Wnt signaling and leads to alopecia due to defects in keratinocyte stem cells.

This study found that HPV16 oncogene expression in multipotent epithelial stem cells led to abnormal mobilization, altering their quiescence without affecting other stem cell markers, suggesting a distinct stem cell compartment.

This review discusses recent progress in understanding the cellular mechanisms of sebaceous gland development and maintenance, emphasizing the role of stem and progenitor cells in related skin pathologies, and reports no new results.

This article argues that lineage labeling with genetic markers is the gold standard for identifying epithelial stem cells, contrary to the view that in vitro methods alone are sufficient.

This study found that dermal papilla-like tissue reconstructed using canine adipose-derived mesenchymal stem cells closely resembles actual canine dermal papilla cells in both morphology and molecular characteristics.

This study found that the E6 gene, but not E7, was responsible for HPV8-induced expansion of keratinocyte stem cells in hair follicle junctional zones in mice.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

This article explores how adult mammals can regenerate hair follicles after wounding and suggests that manipulating cell signals during healing might enhance this process, but provides no new experimental results.

This study found that selective inactivation of ribonucleotide excision repair in mouse epidermis led to spontaneous DNA damage, skin inflammation, and the development of squamous cell carcinoma, suggesting potential implications for cancer development in humans.