July 2023 in “Biomolecules” The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.
May 2018 in “European Journal of Dermatology” Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.
211 citations,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
77 citations,
February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
16 citations,
September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
1 citations,
June 2023 in “Journal of Cosmetic Dermatology” Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.
118 citations,
January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
August 2024 in “International Journal of Molecular Sciences” Mesenchymal Stem Cell therapy shows promise for treating hair loss in Alopecia Areata.
20 citations,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
5 citations,
September 2015 in “PubMed” Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
28 citations,
January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
396 citations,
May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
27 citations,
October 2017 in “British Journal of Dermatology” Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
September 2024 in “Stem Cell Research & Therapy” HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.
July 2009 in “Medical & surgical dermatology” Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.
8 citations,
August 2009 in “Pediatric transplantation” A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.
May 2020 in “Archives of Medical Science” Men with androgenetic alopecia have lower levels of certain proteins and more cell damage.
100 citations,
November 2017 in “EMBO Reports” Metabolic signals and cell shape influence how cells develop and change.
2 citations,
April 2023 in “Stem Cell Research & Therapy” Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
2 citations,
May 2018 in “Expert opinion on orphan drugs” Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
64 citations,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
19 citations,
December 2018 in “Experimental and Molecular Medicine” Small molecule IM boosts hair growth by changing stem cell metabolism.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
1 citations,
February 2023 in “ACS Biomaterials Science & Engineering” The new microwell device helps grow more hair stem cells that can regenerate hair.
224 citations,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
64 citations,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.