April 2019 in “Journal of Investigative Dermatology” Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
411 citations,
April 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
25 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
January 2025 in “International Journal of Biological Macromolecules” Decorin helps hair growth by influencing specific cell signals.
April 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Bald men with male pattern baldness still have hair stem cells, but lack certain cells needed for hair growth.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Estetrol may help prevent hair loss and promote hair growth in women.
316 citations,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
83 citations,
March 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
19 citations,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
8 citations,
July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
7 citations,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
4 citations,
July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
January 2025 in “Antioxidants” SHED-CM can reduce hair graying and protect against damage from X-rays.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.
January 2022 in “Springer eBooks” Using micrografts with stem cells and platelet-rich plasma can safely and effectively help regrow hair.
Yeast extract helps treat hair loss and activates stem cells.
January 1998 in “KAGAKU TO SEIBUTSU” The document suggests that male hormones likely affect hair growth and baldness, and future treatments might involve stem cells and androgen-independent cells.
April 2018 in “Journal of Investigative Dermatology” Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
July 2022 in “Journal of Investigative Dermatology” Skin bacteria help hair regrow by boosting cell metabolism.
January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
262 citations,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
36 citations,
January 2019 in “Nature communications” High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
30 citations,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
16 citations,
May 2011 in “The Journal of clinical investigation/The journal of clinical investigation” Some skin tumors may start from hair follicle stem cells.
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
May 2023 in “International journal of molecular sciences” The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.