174 citations,
November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
67 citations,
June 2018 in “Engineering in Life Sciences” Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
14 citations,
September 2018 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
3 citations,
August 2012 in “Nature Cell Biology” Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
20 citations,
January 2013 in “Cell & Bioscience” Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
10 citations,
November 2022 in “Protein & Cell” Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
13 citations,
September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
9 citations,
June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
66 citations,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
33 citations,
October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
42 citations,
February 2014 in “Stem Cells and Development” Vitamin C helps adipose-derived stem cells grow and may support hair growth.
138 citations,
June 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
21 citations,
January 2018 in “The Korean Journal of Physiology and Pharmacology” Modified stem cells from umbilical cord blood can make hair grow faster.
7 citations,
February 2018 in “InTech eBooks” Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
83 citations,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
9 citations,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
6 citations,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
3 citations,
January 2023 in “Physiological Research” Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
98 citations,
December 2003 in “The FASEB Journal” Thymosin β4 promotes hair growth by activating stem cells in hair follicles.
82 citations,
July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
4 citations,
September 2020 in “Annals of Translational Medicine” Concentrated nanofat helps mice grow hair by activating skin cells and may be used to treat hair loss.
1 citations,
October 2013 Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.
1 citations,
October 2022 in “Scientific reports” Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.