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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Many skin patients also have mental health issues, and doctors should treat both together.

Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Early diagnosis and aggressive treatment are crucial for better outcomes in lymphomatoid granulomatosis.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Probe detects finasteride with high selectivity and low detection limit.

Hair restoration surgery techniques have evolved, with focus on patient selection and realistic goals, and future advancements may include cloning and gene therapy.

Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Recognizing and managing skin-related psychiatric disorders in children is crucial for effective treatment.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Alternative medicine lacks scientific support and relies on the placebo effect, but remains popular and integrated into German healthcare.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

The new classification system for skin disorders emphasizes the importance of understanding a patient's awareness of their condition for better treatment.

Cognitive-behavioral therapy is the best treatment for hair-pulling disorder, and combining it with other therapies could improve results.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Hair-tourniquet syndrome can cause serious toe injuries in infants but can be treated if found early.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.