This study assessed the effectiveness of JAK inhibitors in Jordanian patients with alopecia areata, finding that while both tofacitinib and baricitinib improved SALT scores, baricitinib showed greater improvement and a trend towards better hair regrowth, particularly with longer treatment durations.
May 2025 in “Lithuanian University of Health Sciences” This study found that different diets had a negligible impact on guinea pigs' hair structure and did not significantly alter their health parameters, suggesting both tested diets met their nutritional needs without affecting their well-being.
May 2025 in “Veterinary Medicine and Science” In this study, oral melatonin given to male Pomeranian dogs with Alopecia X improved semen quality and testicular blood flow in a dose-dependent manner, but altered hormonal balance, indicating complex effects that require further investigation for long-term implications.
In this study, human hair dermal papilla cells were incubated with varying concentrations of umbilical cord-derived mesenchymal stem cell exosomes or minoxidil, and cell proliferation was assessed, showing significant results compared to the control.
Ivarmacitinib effectively regrows hair in severe alopecia areata.
April 2025 in “Journal of Cosmetic and Laser Therapy” This study found that QR678 Neo® significantly enhanced hair regrowth, density, and shaft diameter in males with advanced androgenetic alopecia undergoing hair transplant surgery, compared to a conventional method, making it a promising adjunct treatment option.
April 2025 in “Research Square (Research Square)” This study found that microinfusion of minoxidil into the scalp was associated with a reduction in diastolic blood pressure, indicating systemic absorption of the drug.
March 2025 in “Human Genetics and Genomics Advances” This study found that genetic predictions of male pattern baldness from European populations do not generalize well to African populations, highlighting significant differences in genetic architecture between them.
March 2025 in “The Egyptian Journal of Medical Microbiology” This study found that patients with diffuse hair loss had significantly higher serum levels of inflammatory cytokines IL-6 and TNF-α compared to healthy controls, suggesting a potential role of immune system activation in the pathogenesis of this condition.
March 2025 in “Clinical and Experimental Dermatology” In this study, 37.5% of alopecia areata patients treated with tofacitinib were identified as super-responders, with significant predictors for this status being older age and no prior JAK inhibitor treatment, leading to faster and sustained hair regrowth.
This study found that contact dermatitis of the hands, acne, and telogen effluvium were the most prevalent dermatoses among resident doctors during the COVID-19 pandemic, with notable facial post-inflammatory hyperchromia also linked to protective equipment use.
March 2025 in “Acta Dermato Venereologica” This cross-sectional survey found that individuals with alopecia areata and androgenetic alopecia perceived stigmatization and impaired quality of life, with greater stigma reported in German-speaking participants; factors like gender, age, and disease severity influenced stigmatization levels.
March 2025 in “International Journal of Trichology” This study found that, in female patients with pattern hair loss, injections of adipose-derived stem cells increased hair density and thickness, reduced perifollicular inflammation, and enhanced markers associated with hair cycle regeneration.
March 2025 in “Journal of Cosmetic Dermatology” The study found that botulinum toxin-A significantly increased the diameter of the supratrochlear artery in a small patient group, suggesting potential vasodilatory benefits for treating ischemic conditions.
March 2025 in “American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology” This study observed that individuals with hair loss had significantly higher levels of serum galanin, troponin, prolactin, and FSH, and lower levels of TSH, zinc, magnesium, copper, iron, and calcium compared to healthy controls, suggesting a potential role of these biomarkers in hair loss.
February 2025 in “Eduvest - Journal Of Universal Studies” In a laboratory study on guinea pigs, Kepok banana peel extract serum at a 30% concentration showed promising effectiveness for hair growth, with results close to those of 5% minoxidil®, suggesting it could be a viable hair care alternative.
February 2025 in “Clinical & Experimental Dermatology and Therapies” In this randomized trial, oral supplementation with Serenoa repens, pumpkin seed extracts, and cysteine significantly improved the clinical effectiveness of topical 5% minoxidil lotion for treating androgenic alopecia in men and women compared to minoxidil alone, with both treatments being well tolerated.
This study observed that both intradermotherapy with 5% minoxidil and topical minoxidil application resulted in perceived improvements in hair density and thickness among patients with androgenetic alopecia, with no significant difference between the two groups.
January 2025 in “Termometer Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran” In this study, researchers tested a tea leaf ethanol extract (Camellia sinensis) hair tonic and found it increased average hair growth compared to positive and negative controls over 28 days, but exhibited some instability and inhomogeneity after accelerated testing.
January 2025 in “International Journal of Scientific Research in Science and Technology” This study validated an HPLC analytical method for evaluating fenasteride in commercial products, finding it to be sensitive, selective, and within acceptance criteria for specificity, precision, and stability, making it suitable for quality control testing.
January 2025 in “Dermatologic Therapy” This study found that baricitinib significantly reduced alopecia severity in JAK inhibitor-naïve patients compared to those previously treated with tofacitinib, indicating that switching JAK inhibitors can be safe and may be beneficial for selected patients with partial prior responses.
January 2025 in “The Egyptian Journal of Hospital Medicine” This study observed significant repigmentation in localized stable vitiligo lesions treated with oral baricitinib, with even more improvement when combined with topical tacrolimus, and reported no side effects.
January 2025 in “Dermatologic Therapy” This study found that ablative fractional carbon dioxide laser treatment improved skin fibrosis, reduced skin hardening, and enhanced hair follicle growth in localized scleroderma patients, with significant improvements across several clinical measures and no severe adverse effects observed.
January 2025 in “International Journal of Scientific Research” In this study, researchers observed that patients with chronic telogen effluvium residing in fluoride-endemic areas had higher mean serum fluoride levels than those who lived there for less than five years, suggesting a possible link between elevated fluoride levels and increased hair shedding.
December 2024 in “Pakistan Armed Forces Medical Journal” This study observed that Platelet Rich Plasma was significantly more effective than 5% Minoxidil for treating alopecia areata in terms of improving the Severity of Alopecia Tool score.
December 2024 in “Dermatologic Surgery” This study observed that pooled analysis of LED caps increased hair density in patients with androgenetic alopecia compared to sham, achieving 28.5 more hairs per cm².
December 2024 in “Kufa Medical journal” The study reported that patients with alopecia areata had significantly higher serum levels of IL-17A and IL-2 compared to healthy controls, suggesting these interleukins may play an important role in the disease, though they did not correlate with its severity or duration.
December 2024 in “Journal of Dental Panacea” In this retrospective study, QR678 Neo, a biomimetic peptide treatment for androgenetic alopecia, improved hair density by 30% compared to 18% with platelet-rich plasma, with patients reporting higher satisfaction.
Sleep may mediate the link between sugary drinks and female hair loss.
December 2024 in “Journal of Student Research” In this study, the researchers observed that using a shampoo containing hibiscus extract every two days was more effective at reducing hair loss among a small group of cosmetology students compared to using it every three days.