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Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.

Tofacitinib helped a woman with total-body hair loss grow her hair back.

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Enz_MoriL from mulberry leaves helps hair growth by affecting specific cell pathways.

Circular RNA ERCC6 helps activate stem cells important for cashmere goat hair growth by interacting with specific molecules in an m6A modification-dependent way.

TRPV3 in skin cells causes inflammation and cell death.

Activating TRPV3 reduces skin oil production and increases inflammation, potentially causing dry skin issues.

IFN-γ and IL-2 are important for T cell activation in hair loss in mice.

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

Lower SMAD2/3 activation predicts more severe skin cancer.

Storing hair follicle micrografts for longer times can cause them to enter a state similar to the natural hair shedding phase, which might impact hair transplant results.

Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.

Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.

RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

Platycladus orientalis leaf extract helps hair grow by activating certain proteins.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.