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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Targeted cancer therapies often cause serious skin problems that need careful management.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Zinc is effective for treating various skin conditions, including warts and acne.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

No treatment fully prevents hair loss from chemotherapy yet.