66 citations
,
January 2001 in “Vitamins and hormones” This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.
56 citations
,
February 2006 in “American journal of physiology. Cell physiology” This study observed that in hormone-starved prostate cancer cells, the androgen 5alpha-dihydrotestosterone rapidly induces matriptase activation and shedding, which involves androgen receptor signaling and requires both transcription and protein synthesis.
55 citations
,
October 2009 in “Clinics in Plastic Surgery” Burn reconstruction improves with new techniques, materials, and tissue engineering.
54 citations
,
August 2009 in “Dermatologic Surgery” This review outlines the steps of contemporary hair transplantation surgery, including the roles of medications and nonsurgical options, but it reports no new clinical findings.
54 citations
,
September 2005 in “Australasian Journal of Dermatology” This study found that general practitioners' diagnostic accuracy for skin conditions aligned with histological diagnosis in 24% of cases, whereas dermatologists achieved 77% concordance.
51 citations
,
January 2004 in “Domestic animal endocrinology” This study concluded that an endogenous circannual rhythm of prolactin secretion in mouflon influences their seasonal hair growth and moulting cycle, which varies under different photoperiodic and melatonin treatments.
50 citations
,
November 2010 in “Plastic and Reconstructive Surgery” This study suggests that Botox injections may increase hair count and reduce hair loss in men with androgenetic alopecia, potentially through increased blood flow and oxygen to the scalp.
46 citations
,
September 2011 in “Journal of Endocrinology” This study suggests that 5α-reduced glucocorticoids may have anti-inflammatory potential and could serve as biomarkers for liver inflammation in metabolic disease, with implications for drug development.
45 citations
,
January 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that overexpression of AKR1C3 in prostate cancer cells redirected androgen metabolism towards testosterone production, which facilitated cell proliferation, potentially reducing the effectiveness of finasteride treatment.
41 citations
,
October 2024 in “Nature Communications” In this study, researchers developed a wearable red and blue LED patch and a sprayable fibrin gel to treat infected wounds at home, demonstrating effective infection control and enhanced wound healing in diabetic mice and minipigs.
40 citations
,
January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.
40 citations
,
December 1980 in “The Journal of Dermatologic Surgery and Oncology” This review describes an improved scalp reduction technique that removes two to three times more bald skin than previous methods, utilizing wide undermining, serial relaxing incisions, and adrenocorticosteroids.
35 citations
,
April 2014 in “Journal of proteomics” In this study, experimentally induced weight loss in merino sheep led to a decrease in wool fiber diameter and increased expression of certain high sulfur and glycine-tyrosine proteins, potentially impacting wool quality and industry preferences.
34 citations
,
January 2015 in “Biomedicine and Biotechnology” This review discusses how mineral deficiencies, particularly iron and zinc, affect health globally and explores bio-fortification and other strategies to combat these deficiencies, but reports no new experimental results.
32 citations
,
July 2018 in “Scientific Reports” In this study, the authors reported that feeding cashmere goats with essential oil-cobalt significantly enhanced their growth, meat quality, and fiber quality, while stimulating immune-related physiological changes.
30 citations
,
January 2016 in “Journal of Pharmaceutical and Biomedical Analysis” This study identified trilauric glyceride and decanoylcarnitine as potential biomarkers for diagnosing PCOS in patients with and without insulin resistance, suggesting significant metabolic alterations in these conditions.
30 citations
,
January 2013 in “Obesity Surgery” This review summarizes the effects and complications of bariatric surgery on skin, noting it can alter existing skin conditions like psoriasis and trigger new dermatoses, but provides no new clinical results.
26 citations
,
November 2016 in “European Journal of Clinical Pharmacology” This study found that using valproic acid during radiotherapy for glioma was associated with delayed hair loss and improved survival outcomes.
26 citations
,
October 2012 in “Dermatologic Clinics” This article reviews recent advancements in hair transplantation techniques, particularly follicular unit transplantation, and suggests an expansion of its applications beyond male pattern hair loss, but reports no new results.
26 citations
,
January 1994 in “Clinics in Dermatology” This article reviews advancements in burn care, emphasizing early wound excision's role in decreasing morbidity and mortality, but it reports no new clinical findings.
25 citations
,
July 2021 in “Journal of Medical Virology” This review focuses on the various skin symptoms associated with COVID-19 but reports no new clinical findings.
25 citations
,
January 2009 in “Oral and Maxillofacial Surgery Clinics of North America” This article reviews complications associated with modern hair transplant surgery and discusses their treatment and prevention but reports no new clinical results.
24 citations
,
July 2015 in “Biogeosciences” This study found that the growth of hair ice on dead wood requires the biological activity of a winter-active fungus, specifically Exidiopsis effusa, which shapes and stabilizes the ice structures.
24 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses potential complications in surgical hair restoration and emphasizes the importance of both patient and physician actions in minimizing these risks; it reports no new results.
23 citations
,
May 2019 in “Expert Opinion on Therapeutic Patents” This review discusses AR-modulating agents developed between 2012 and 2018, highlighting challenges with ligand-binding domain antagonists and proposing nonconventional approaches targeting other domains as promising strategies.
23 citations
,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” This study demonstrated that a 3D air–liquid culture system using Wnt-CM-treated cells can induce hair regeneration in nude mice and may facilitate large-scale preparation for hair loss treatment.
23 citations
,
March 2001 in “Clinics in Dermatology” This article reviews treatment options for male androgenetic alopecia, including minoxidil, 5 alpha reductase inhibitors, and hair transplantation, but reports no new clinical findings.
21 citations
,
October 2008 in “Indian Journal of Plastic Surgery” This article discusses recent advancements in hair transplantation techniques that combine art and science for more natural results, but reports no new clinical findings.
21 citations
,
September 1979 in “Archives of Otolaryngology-head & Neck Surgery” This article reviews the use of the Juri procedure for transferring hair to bald scalps, achieving satisfactory cosmetic results in all patients over two years, but reports no new clinical findings.
19 citations
,
December 2015 in “European Journal of Human Genetics” This study found that a novel rare variant in ITGB6 may cause intellectual disability, alopecia, and dentogingival anomalies in a specific Pakistani family, highlighting a potential role for ITGB6 beyond enamel formation.