June 2023 in “Benha Journal of Applied Sciences” In this study, researchers isolated gram-positive bacteria from acne lesions in 50 patients, finding that Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus, and Leuconostoc mesenteroides were present at varying frequencies, indicating multimicrobial causes for acne vulgaris.
April 2023 in “Journal of Investigative Dermatology” This study found that the type 2 cytokines IL-4 and IL-13 may amplify Staphylococcus aureus-induced inflammation and barrier disruption in atopic dermatitis, potentially worsening skin defense against this bacterium.
January 2023 in “Fundamental toxicological sciences” In this study, mozuku-derived ultra-high-molecular-weight fucoidan was found to inhibit the growth of skin bacteria like Staphylococcus aureus but not other tested bacteria such as Cutibacterium acnes.
November 2022 in “Journal of Investigative Dermatology” This study found that sodium butyrate, a metabolite from the HF microbiome, significantly delayed catagen onset and promoted key physiological processes in cultured human hair follicles.
January 2022 in “Journal of pharmacognosy and phytochemistry” This study found that a polyherbal gel made from guava leaves, amla, and aloe is effective against candidiasis on the skin, with additional benefits of nourishing hair and preventing premature graying.
September 2021 in “Pediatrics in review” This case study describes a 7-month-old boy diagnosed with keratitis-ichthyosis-deafness syndrome due to a de novo GJB2 gene mutation, highlighting the challenges in treatment and eventual fatal outcome due to severe complications.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
May 2021 in “British Journal of Dermatology” This review discusses the composition and role of the hair follicle microbiome in health and disease, highlighting that our understanding remains limited and stressing the need for more comprehensive studies.
April 2021 in “Journal of Investigative Dermatology” This study found that CD1a-restricted CD4+ T cells responsive to lysyl-phosphatidylglycerol were more frequent in the blood of atopic dermatitis patients, suggesting a potential role in the disease's Th2-mediated pathology.
July 2020 in “International journal for research in applied science and engineering technology” This study reports that a newly formulated herbal shampoo using natural ingredients like fenugreek and shikakai was successfully developed to eliminate harmful synthetic components in anti-dandruff shampoos.
January 2020 in “Social Science Research Network” This study found that skin bacteria contribute to regeneration in wound healing and WIHN by promoting IL-1β signaling, challenging the view that sterility is always beneficial for healing small wounds.
May 2019 in “Eurasian Journal of Biosciences” In this study, researchers observed that fenugreek aqueous extract was more effective than its alcohol extract in inhibiting the growth of bacteria associated with acne, particularly gram-positive bacteria like Staphylococcus epidermidis and Staphylococcus aureus.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.
September 2018 in “Practical diabetes” This article reviews various skin conditions and infections associated with diabetes, noting that people with diabetes are at higher risk for skin conditions such as cellulitis, folliculitis, and skin cancer, and reports no new clinical results.
July 2018 in “British Journal of Dermatology” Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.
April 2018 in “Journal of Investigative Dermatology” This study found that in obese mice, local antimicrobial activity is reduced due to a loss of adipogenic stem cells and an increase in mature adipocytes, leading to higher susceptibility to skin infections.
This study reports that a specific transporter protein in Staphylococcus hominis is responsible for transporting a malodour precursor, thereby playing a key role in human body odor production.
February 2018 in “Trends in Immunology” This study demonstrated that antigens from the skin bacterium Staphylococcus epidermidis can stimulate CD8+ T cells, which in turn enhance wound healing.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study using a genetic mouse model found that S. aureus-driven dysbiosis sustains inflammatory skin side effects from EGFR inhibitors, suggesting prophylactic antibiotic treatment may reduce rash severity without fixing barrier defects.
August 2017 in “Journal of Investigative Dermatology” Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
April 2017 in “Australasian Journal of Dermatology” This study observed that systemic acitretin improved symptoms in 75% of lichen planopilaris patients, despite varied responses and a dominant female prevalence.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
April 2017 in “Journal of Investigative Dermatology” In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.
April 2016 in “Journal of Investigative Dermatology” This study found that both topical tretinoin and oral isotretinoin altered the free fatty acid profile of sebum in acne patients, affecting bacterial growth differently for S. epidermidis and S. aureus.
January 2016 in “Dermatology Online Journal” This case report describes a pregnant woman who developed bullous impetigo, which resolved after treatment with clindamycin, suggesting that this condition should be considered in similar blisters in pregnant women.
June 2014 in “Zagazig Journal of Pharmaceutical Sciences/Zagazig Journal of Pharmaceutical Science” This study reports that using ascorbic acid or orlistat can significantly inhibit the metabolism of testosterone esters into malodorous metabolites by axillary bacteria, suggesting potential new deodorant applications.
This study found that hair cosmetics have strong bacteriostatic properties, suggesting that current microbial test methods for these products should be revised.
October 2012 in “International journal of child health and human development” This article reviews common adolescent skin conditions and their management in primary care, but it does not report new clinical findings.
July 2011 in “British Journal of Dermatology” Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.
October 2007 in “Journal of Investigative Dermatology” The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.