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Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Oxidative stress contributes to hair graying and loss as we age.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Fat cells in the skin help start healing and form important repair cells after injury.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Liposomes could improve how skin care products work but are costly and not very stable.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

PRP injections improve hair thickness for baldness.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.