Cicatricial alopecia can progress to complete hair loss, making diagnosis and management difficult.
120 citations
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November 2014 in “Biological Reviews” This article explores the dynamic and energy-efficient nature of telogen hair follicles, challenging the notion of dormancy, and highlights their potential in advancing treatments for hair growth disorders.
61 citations
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January 2011 in “PloS one” In this study, researchers found that Notch signaling is crucial for late-stage epidermal differentiation and postnatal hair cycle homeostasis by regulating hair follicle stem cell proliferation and differentiation.
28 citations
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June 1994 in “Journal of Dermatological Science” This study found that proteolytic activities in murine skin vary with hair cycle stages, with significant collagenase activity during the early anagen phase.
23 citations
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December 1995 in “Archives of Dermatology” This case report discusses a 32-year-old man's treatment for advanced androgenetic alopecia using a combination of topical minoxidil and oral finasteride, but no clinical outcomes are detailed.
11 citations
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October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
3 citations
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July 2020 in “International Journal of Molecular Sciences” This study reported that molecules from Zebrafish embryo cell differentiation can counteract neurodegeneration, regenerate tissues, and potentially reverse hair follicle damage in androgenetic alopecia.
3 citations
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February 2016 in “Nature Biotechnology” New drug shows promise for better hair growth in baldness treatment.
2 citations
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February 2024 in “International Journal of Molecular Sciences” This study reported that in a mouse model, Negative Pressure Wound Therapy promotes wound healing by modulating inflammatory responses and increasing dickkopf-related protein 1, which encourages the differentiation of Hair Follicle Stem Cells into epidermal cells.
1 citations
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December 2014 in “Zenodo (CERN European Organization for Nuclear Research)” This protocol details a method for inducing skin cancer in mice through chemical carcinogenesis, which studies cutaneous malignancies but does not report new findings.
1 citations
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November 2014 in “Journal of Biomedical Optics” This study introduced a noninvasive spectroscopy method to assess hair follicle stages in mice by measuring skin diffuse reflectance and melanin dynamics, offering a potential tool for hair regeneration research.
1 citations
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December 1995 in “Archives of Dermatology” This case report describes a patient with advanced androgenetic alopecia who underwent a 6-month trial of topical minoxidil and oral finasteride, aiming to optimize hair regrowth without surgery.
EfficientNet improves accuracy in diagnosing hair loss stages.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper documents a case of natural reversal of moderate-to-severe androgenetic alopecia without medical intervention, but emphasizes it is an individual observation not generalizable to broader populations.
February 2026 in “International journal of intelligent engineering and systems” This study proposes a new method for hair segmentation that improved performance in skin lesion images, as indicated by an increase in the Dice score from 76.97% to 79.08%.
This study investigated the molecular mechanisms behind cashmere goat coat types by analyzing gene expression during hair follicle development stages, identifying regulatory pathways involved in metabolism, immune response, and the quiescent state of follicles, potentially aiding in genetic selection for improved cashmere production.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this documented case report, the researcher detailed a natural reversal of moderate-to-severe androgenetic alopecia without any medical interventions by systematically observing and analyzing hair regrowth over time, emphasizing that these findings are purely from personal practice and not applicable to broader populations.
January 2025 in “BMC Pediatrics” In this study conducted among healthy Iranian girls in Isfahan province, researchers found that the median onset age for menstruation was 12.05 years, breast development began at 9.89 years, and pubic hair development started at 10.14 years, with earlier puberty onset potentially indicating precocious puberty.
June 2024 in “ESMO Gastrointestinal Oncology” The BAYONET trial is a phase II study designed to assess the efficacy and safety of combining encorafenib, binimetinib, and cetuximab for patients with BRAF V600E-mutant metastatic colorectal cancer that is resistant to encorafenib plus cetuximab; results are not yet reported.
October 2021 in “Research Square (Research Square)” This study found that gene expression patterns can effectively distinguish the cashmere growth cycle stages and highlight molecular pathways, suggesting melatonin's role in regulating cashmere growth in Inner Mongolian goats.
June 2021 in “Research Square (Research Square)” This study reports that melatonin influences gene expression related to cashmere growth cycles in Inner Mongolian cashmere goats, potentially aiding in understanding and enhancing cashmere yield through molecular regulation.
September 2011 in “Hair transplant forum international” This commentary discusses the ongoing debate about the advisability of initiating hair transplants in people with early-stage male or female pattern baldness and does not present new research findings.
March 2005 in “Journal of the American Academy of Dermatology” Bexarotene 1% topical gel helped some patients with alopecia areata regrow hair.
October 2021 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this hospital-based cross-sectional study, researchers observed that trichoscopy effectively differentiates between severe and mild male pattern hair loss by identifying specific features such as yellow and white dots, vellus hair, and hair shaft diversity.
375 citations
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July 2006 in “Journal of Investigative Dermatology” This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.
55 citations
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August 2013 in “PloS one” This study suggests that changes in expressed transcripts and splice isoforms may explain the transition from curly to straight fleece in Chinese Tan sheep as they age.
24 citations
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January 2006 in “Skin Pharmacology and Physiology” This study found that finasteride (1 mg/day) appeared to reverse the shortening of the hair cycle in androgen sensitive sites but did not convert miniaturized hair into terminal hair.
14 citations
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January 2018 in “Scientific reports” This study demonstrated that bioluminescence imaging of NG2+ cells in transgenic rats allows in vivo monitoring of hair follicle cycles to study hair growth and follicle regeneration.
12 citations
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December 2020 in “Archives animal breeding/Archiv für Tierzucht” This study found that EDA and EDAR are expressed throughout cashmere goat fetal development and play a critical role in hair follicle formation by influencing gene expression in fibroblasts and epithelial cells.
9 citations
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February 2022 in “BMC Genomics” This study examined gene expression in cashmere goats and identified key pathways and molecular regulators that influence hair follicle growth stages and melatonin's role in promoting cashmere growth.