This study reports that carbamazepine can self-assemble into stable channel structures without guest polymers, while griseofulvin relies on guest molecules for structural stability in drug-polymer inclusion complexes.
This study investigated the molecular mechanisms behind the formation of drug-polymer inclusion complexes and found that carbamazepine can self-assemble into stable channel structures without guest polymers, unlike griseofulvin, which requires guest molecules for structural stability.
This research elucidates the molecular mechanisms underlying carbamazepine and griseofulvin's inclusion complex channel formations with polymers, revealing why carbamazepine forms stable channels independently, while griseofulvin requires polymeric support due to weaker interactions.
August 2022 in “Research Square (Research Square)” This study found that implanting HAP stem cells in a mouse model accelerated wound closure and reduced scar formation, suggesting potential for scar-free wound healing.
January 2021 in “arXiv (Cornell University)” This study found that self-supervised pretraining significantly improves accuracy in medical image classifiers for dermatology and chest X-ray tasks, outperforming supervised baselines and showing robustness to distribution shifts with limited labeled data.
April 2020 in “Research Square (Research Square)” This study found that exosomes derived from human bone marrow mesenchymal stem cells significantly promote cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
April 2019 in “University of Huddersfield Repository (University of Huddersfield)” This study explored the experiences of adolescents with alopecia and their parents, highlighting the emotional distress caused by the condition and the inadequate response of healthcare professionals to their needs.
January 2019 in “LASER THERAPY” Laser technologies improve medical treatments and outcomes.
May 2018 in “White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)” In this study, researchers found that alopecia areata patients show a significant reduction in suppressive regulatory T-cells and an increase in inflammatory T-cell populations, suggesting an immunological imbalance contributing to the disease.
April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)” This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.
September 2017 in “Indian Journal of Plastic Surgery” This study presents an economical and user-friendly training module using common materials and goat skin to teach the steps of the strip method for hair follicle harvesting and implantation.
September 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that high-speed optical coherence tomography may be a promising non-invasive tool for analyzing human hair conditions.
December 2011 in “The Diabetes Educator” This article describes how a new blood glucose management service at the NIH Clinical Center improved safety and patient outcomes for hospitalized patients with diabetes.
May 2009 in “The American Journal of Dermatopathology” This abstract contains only journal subscription and informational content and does not present any research findings.
August 2016 in “InTech eBooks” This source highlights the diverse scope of facial plastic and reconstructive surgery, noting the specialty's adaptability to changing trends and ethnic preferences for aesthetic outcomes, without reporting specific study results.
788 citations
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February 2007 in “Nature” This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.
773 citations
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August 2017 in “International Journal of Molecular Sciences” This article reviews the potential advantages of secretome derivatives from human uterine cervical stem cells in MSC therapy and notes the need for regulatory standards to ensure safety and efficacy.
405 citations
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May 2007 in “Journal of The American Academy of Dermatology” This review discusses the profound impact of obesity on skin physiology and dermatologic conditions and reports no new experimental results, recommending awareness and treatment strategy development for obesity-associated dermatoses.
343 citations
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March 2016 in “Nature Communications” This study found that IL-17A-producing γδ T cells play a key role in bone fracture healing by promoting bone formation, with deficiencies leading to impaired repair in mice.
192 citations
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April 2019 in “ACS nano” In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
191 citations
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February 2002 in “Archives of Dermatology” This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.
117 citations
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November 2006 in “Experimental Dermatology” This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.
100 citations
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September 1999 in “British Journal of Dermatology” This study suggests that finasteride's effect on promoting hair growth in men with androgenetic alopecia may be due to its inhibition of 5aR2 localized in hair follicles.
93 citations
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November 2018 in “Carbohydrate Polymers” This study demonstrated that modified montmorillonites combined with bacterial cellulose enhanced antimicrobial, wound healing, and tissue regenerative activities in a burn mice model, suggesting potential as an artificial skin substitute for burn patients.
90 citations
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January 2021 in “Clinical Endocrinology” This review discusses the impact of weight gain and obesity on the development of polycystic ovary syndrome and explores lifestyle strategies to manage the condition, without reporting new clinical results.
87 citations
,
March 2020 in “Australian Dental Journal” This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.
86 citations
,
April 2016 in “Nature Communications” This study suggests that Notch1 acts as a key signal in skin epithelium, promoting immune cell recruitment and aiding in normal skin repair after damage.
71 citations
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February 2006 in “Clinics in Dermatology” This review discusses the physiological skin changes during pregnancy and reports no new clinical results, emphasizing the importance of distinguishing these changes from pathological conditions.
70 citations
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February 2021 in “International Journal of Molecular Sciences” This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.