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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

Hair color and length affect metabolite profiles in hair, so they should be considered in hair analysis.

New method measures finasteride in blood quickly and accurately.

Scalp hair grows at 0.37 mm/day, forearm hair at 0.18 mm/day, and thigh hair at 0.30 mm/day, with no significant differences found in people with certain hair conditions.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Hair analysis is better than urine and blood for detecting past drug use.

Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.

Quick, selective detection of tadalafil and finasteride in human plasma developed.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Forensic hair analysis for drugs is now more reliable and accurate.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.

Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

Ancient herders in the Keriya Valley fed their animals mainly C3 plants, with some C4 plant feeding possibly due to herd movement or seasonal changes.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

The new skin cream with FOL-005 safely promotes hair growth and is stable and user-friendly.

Silver oxide nanoparticles help detect small molecules effectively.

Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Higher testosterone and DHT levels are linked to hair loss in men, but not to prostate cancer risk.

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.