21 citations
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October 2023 in “The Journal of Physical Chemistry C” This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.
17 citations
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May 2023 in “Pharmaceutics” This review highlights the potential of microneedles for immunotherapy, emphasizing their ability to enhance immune responses and reduce side effects through precise and stimuli-responsive delivery, especially in tumor treatment, while also noting the limitations and areas for improvement in current systems.
1 citations
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March 2022 in “Journal of Dermatological Science” This study concluded that overexpressing TERT and BMI1 in cultured human dermal papilla cells extended their lifespan and enhanced their ability to induce hair growth in mice.
This review highlights the potential of microneedles as a pediatric-friendly method for delivering proteins, vaccines, and diagnostics transdermally, noting their ability to penetrate the skin's barrier and suggesting future applications in other parts of the body.
August 2025 in “Plastic and Aesthetic Research” This review discusses recent advancements in microneedle technology for hair loss treatment, highlighting their ability to enhance drug delivery and improve hair follicle survival in transplantation, while also exploring their potential integration with tissue engineering to address regeneration challenges.
August 2026 in “Pharmaceuticals” This review reports that biopolymer-based hydrogels show promise as wound dressings due to their biocompatibility, moisture retention, and ability to mimic the extracellular matrix, though challenges in mass production, safety, and clinical validation remain.
September 2025 in “Deleted Journal” This study found that in vitro environments simulating testosterone levels in elderly males, testosterone and its metabolite DHT significantly reduced macrophages' ability to phagocytize MRSA and Pseudomonas aeruginosa, suggesting AR manipulation and inhibiting testosterone-DHT conversion might help fight wound infections in the elderly.
36 citations
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August 2020 in “Polymers” The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.
9 citations
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November 2024 in “Biotechnology for Sustainable Materials” This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.
8 citations
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May 2025 in “Biomimetics” In this review, cellulose-based nanofibers are highlighted for their potential in wound care, given their biodegradability, biocompatibility, and ability to enhance antimicrobial properties and drug delivery in wound dressings through modern fabrication techniques like electrospinning.
1 citations
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January 2024 in “Scientific reports (Nature Publishing Group)” This study explored using keratin extracted from human hair waste to create biodegradable bioplastic films, revealing promising potential for applications in packaging and disposable items due to their uniform surface morphology and ability to degrade with keratinophilic fungi.
October 2024 in “Applied Sciences” In this study, tubular 3D bioprinted structures made from sodium alginate and gelatin, containing NIH/3T3 fibroblast cells, demonstrated the ability for cell growth and network formation over 6 weeks, although structural tensile strength decreased with cell growth and polymer degradation.
3 citations
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April 2025 in “Advanced Healthcare Materials” In this study, researchers developed hyaluronic acid derivatives functionalized with nitric oxide photodonors for light-activated skin treatments, finding that the compounds released NO under blue light and enhanced keratinocyte proliferation and migration, suggesting potential for therapeutic use.
1 citations
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April 2023 in “Scientific Reports” This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that formulation F6 of the tested creams had superior stability and antioxidant potential, making it the most effective among the formulations.
January 2025 in “Advanced Materials Interfaces” This study observed that tannic acid significantly reduced hair shedding by 56.2% over seven days in human participants when used as a coating for controlled release of active compounds to hair follicles.
517 citations
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February 2010 in “Materials” This review discusses the history and development of keratin biomaterials for biomedical uses, highlighting their biological activity and biocompatibility, and provides no new research findings.
30 citations
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February 2023 in “Biomaterials Research” This study evaluated a new carboxymethyl chitosan/polyaldehyde dextran (CMCS/PD) hydrogel and found it to be a promising tissue adhesive for trauma emergencies in rats, showing rapid gel formation, strong adhesion, and better antibacterial properties than some commercial alternatives.
37 citations
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December 2018 in “Frontiers in Immunology” This study found that fibroin/gelatin and spidroin microparticles increased re-epithelialization rates and inhibited scar formation in mouse models of deep skin wounds.
2 citations
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August 2022 in “Frontiers in Veterinary Science” This study constructed a ceRNA regulatory network related to cashmere goat secondary hair follicle development, highlighting the role of circRNA in their morphogenesis through the ceRNA mechanism.
1 citations
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October 2025 This source describes wound healing as a complex biological process that requires precise regulation and coordination among various cells, cytokines, and signaling pathways to achieve tissue repair, although specific findings or results are not provided in the abstract.
4 citations
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February 2015 in “PubMed” This study found that a minoxidil foamable emu oil emulsion significantly promoted hair growth in animals compared to a marketed 5% minoxidil solution, showing increased hair follicles in the anagenic phase.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a polyherbal powder shampoo formulated from Ayurvedic medicinal plants, determining that formulation F3 performed best in cleansing, conditioning, and scalp protection, offering a sustainable and effective alternative to synthetic shampoos.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the development of a herbal anti-dandruff shampoo using natural ingredients like fenugreek, curry leaves, and neem, finding it effective in reducing dandruff and nourishing the scalp without causing irritation, and suggesting it as a safe and economical alternative to synthetic shampoos.
14 citations
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March 2015 in “Stem Cell Research & Therapy” This study indicates that ABCG2 expression identifies interfollicular keratinocyte progenitor cells in human epidermis and suggests it could help enrich these stem cells for research and treatment.
December 2025 in “Sensors” In this review, recent advances in long-acting microneedle-based transdermal drug delivery systems are outlined, highlighting biodegradable polymers like PLA, PLGA, and PCL for sustained release and discussing challenges in clinical translation such as consistency in manufacturing and validating long-term efficacy and safety.
17 citations
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January 2016 in “Journal of Drug Delivery” In this study, PEG and keratin scaffolds selectively influenced protein release rates based on charge and size, suggesting their potential for targeted delivery of protein therapeutics.
67 citations
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June 2019 in “Proceedings of the National Academy of Sciences” This study introduces a method for long-term expansion of adult mouse epidermal stem cells in vitro using an organoid culture system that maintains the basal-apical organization.
41 citations
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September 2021 in “Materials” This review discusses the role of biomaterials and colloidal drug delivery systems in promoting tissue regeneration within regenerative medicine, but it reports no new clinical results.
22 citations
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November 2023 in “Molecules” This review focuses on recent advances in smart responsive polymer microneedles, which offer precise, on-demand drug delivery triggered by external or physiological stimuli, highlighting significant research implications for transdermal drug administration according to this source.