research Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study
Optimized film improves finasteride skin absorption and treatment efficiency.
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research UHPLC/Q-TOFMS-Based Plasma Metabolomics of Polycystic Ovary Syndrome Patients With and Without Insulin Resistance
The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.
research Removing All Obstacles: A Critical Role for p53 in Promoting Tissue Renewal
The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
research Androgenetic Alopecia: Treatments and Efficacy
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
research Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy
Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
research Keratin and Skin Disorders
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
research Health-Related Quality of Life Questionnaire for Polycystic Ovary Syndrome (PCOSQ-50): Development and Psychometric Properties
The PCOSQ-50 is a valid and reliable questionnaire for measuring quality of life in Iranian women with PCOS.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Solid Lipid Nanoparticles Suspension Versus Commercial Solutions for Dermal Delivery of Minoxidil
SLN suspensions work as well as commercial solutions for minoxidil delivery, but are non-corrosive, making them a promising alternative.
research Artificial Skin for Wound Healing
Artificial skin is improving wound healing and shows potential for treating different types of wounds.
research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies
Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
research Therapeutic Applications and Pharmacoeconomics of Microneedle Technology
Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
research Complications in Hair-Restoration Surgery
Hair restoration surgery can have complications; success depends on patient education, careful planning, and proper execution.
research Ganoderma Lucidum as an Inhibitor of Testosterone-Induced Prostatic Hyperplasia in Rats
Ganoderma lucidum may help treat enlarged prostate in rats.
research A Sport Crisis Typology: Establishing a Pathway for Future Research
The document concludes that future research should focus on tailored solutions for managing sports crises and consider legal and cultural factors.
research The Therapeutic Use of Topical Contact Sensitizers in Benign Dermatoses
Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.
research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses
Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.
research Procyanidins Attenuate Neuropathic Pain by Suppressing Matrix Metalloproteinase-9/2
Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
research Minoxidil in Breast Milk
Minoxidil in breast milk may harm nursing infants.
research Injectable Silver Nanoclusters-Based Hydrogel for Wound Healing by Eliminating Bacterial Infection and Promoting Tissue Regeneration
The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
A new method extracts red dyes from wool without damaging it, although it slightly weakens the wool.
research Shampoos And Hair Conditioners
Good haircare and communication with doctors are key for managing hair loss.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Modeling Cell-Cell Communication for Immune Systems Across Space and Time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Reactive Keratin Derivatives: A Promising Strategy for Covalent Binding to Hair
Modified keratin binds better to hair, especially bleached hair.
research Gender Differences in Skin Aging and the Changing Profile of the Sex Hormones with Age
The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.