17 citations
,
June 2023 in “Pharmaceuticals” In this study, researchers found that people with Parkinson's disease showed higher levels of inflammasome proteins, including caspase-1, ASC, and IL-18, compared to healthy individuals, suggesting these proteins as reliable biomarkers for inflammation in PD.
This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.
5 citations
,
May 2020 in “Diagnostics” This study involving male patients with androgenic alopecia found that a higher baseline zinc plasma level, specifically above 10 µmol/L, may predict the success of treatment with 5% topical minoxidil, correlating with increased hair density and diameter in the parietal area.
November 2025 in “Urology” This study found that the Mark Cuban Cost Plus Drug Company offers significant cost savings on men's health medications compared to both Medicare and GoodRx, particularly for erectile dysfunction treatments.
This study observed that adherence to finasteride treatment in patients with benign prostatic hyperplasia at a clinic in Tepic Nayarit had not been previously evaluated in Mexico.
13 citations
,
April 2024 in “International Journal of Molecular Sciences” This literature review highlights the importance of understanding the mechanisms behind the gradual mosaic loss of the Y chromosome (mLOY) in men, its association with various health conditions like cardiovascular diseases and cancer, and its potential as a marker for age inference.
65 citations
,
October 2018 in “Frontiers in cellular and infection microbiology” This study observed that dandruff in Indian women is associated with a distinct scalp microbiome, including specific bacterial and unknown Malassezia species, with implications for nutrient homeostasis and cell-host adhesion pathways.
39 citations
,
October 2010 in “Journal of The American Academy of Dermatology” This study reported that alopecia occurred in 2.5% of patients with mycosis fungoides or Sézary syndrome, with some cases resembling alopecia areata and others associated with specific skin lesions.
29 citations
,
August 2005 in “Biopolymers” In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.
25 citations
,
May 2019 in “Heliyon” This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.
16 citations
,
October 2003 in “Journal of applied polymer science” This study found that chemically modifying hair with 2-iminothiorane hydrochloride improved the permanence of hair setting without damaging the hair by increasing disulfide bonds.
14 citations
,
September 2016 in “Journal of Photochemistry and Photobiology B Biology” This study observed that mercury-lamp irradiation may cause cleavage of disulfide bonds in keratins of white hair, leading to the formation of thiols in laboratory settings.
12 citations
,
October 2016 in “Anais Brasileiros de Dermatologia” This review discusses the increasing reports of frontal fibrosing alopecia, a form of scarring alopecia, and its potential link to autoimmune disorders, but reports no new clinical results.
11 citations
,
September 1996 in “Journal of applied polymer science” In this study, treatment with aqueous KCN selectively converted disulfide bonds to monosulfide crosslinks in hair, leading to changes in microstructural properties and rubberlike elasticity under specific laboratory conditions.
4 citations
,
January 2015 in “Sen'i Gakkaishi” This study proposed a network model for the cross-linked structure of keratin-associated proteins in hair and wool fibers, suggesting notable differences between the two, potentially affecting hair fiber elasticity.
2 citations
,
June 2017 in “Journal of Evidence Based Medicine and Healthcare” This study found diverse clinical presentations in patients with newly detected connective tissue disease, highlighting the diagnostic and prognostic importance of cutaneous features.
1 citations
,
April 2014 in “Dong-ui saengni byeongni hakoeji/Dong'ui saengli byeongli haghoeji” This study indicates that Samhwang-Sasimtang ethanol extract may promote hair growth in a mouse model, showing stronger effects than a control but less than 3% minoxidil.
January 2026 in “Forum Dermatologicum” This study observed that 2.5% of patients with mycosis fungoides or Szary syndrome experienced alopecia, predominantly within skin lesions, with scalp metastases from other cancers also potentially causing hair loss, highlighting the diagnostic value of trichoscopy in differentiating alopecia types.
October 2023 in “Journal of the Endocrine Society” This case report highlights that Sheehan's syndrome can still occur in developed countries due to factors like migration and delayed diagnosis, with diabetes insipidus sometimes masked by adrenal insufficiency.
March 2023 in “European journal of internal medicine” This case study highlights a delayed diagnosis of Sheehan's syndrome in a woman with post-partum hemorrhage history, emphasizing the importance of considering non-specific symptoms and menstrual history for diagnosis.
October 2022 in “Frontiers in Endocrinology” This review discusses recent advancements in omics and gene editing technologies for studying neuropeptides and receptors in fish, but reports no new experimental findings; the authors highlight the need for further research in this area.
May 2022 in “Journal of Neurology Neurosurgery & Psychiatry” This case report highlights the overlap of Sjögren’s Syndrome and Systemic Lupus Erythematosus, noting major salivary gland enlargement and bilateral facial nerve involvement, which may better explain the patient's symptoms than lupus alone.
This case report details a child with a specific TNFAIP3 mutation manifesting as a severe SLE/SS phenotype, expanding the known phenotype for this genetic variant.
June 2015 in “Annals of the Rheumatic Diseases” This clinical case report describes a 44-year-old male whose initial diagnosis of rheumatoid arthritis progressed over a decade to include systemic lupus erythematosus and Sjögren's Syndrome, highlighting the complexity of managing multiple autoimmune syndromes.
April 2014 in “동의생리병리학회지” This study found that Samhwang-Sasimtang herbal extract may enhance hair growth in mice, as indicated by increased hair follicle activity and reduced growth inhibition factors compared to a control.
71 citations
,
September 2013 in “Materials Science and Engineering C” Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.
52 citations
,
February 2005 in “Biopolymers” In this study, chemical treatments during permanent hair straightening were found to randomize proteins in the cortex, aiding in the reconnection of disulfide bonds during oxidation.
6 citations
,
March 2023 in “Materials” In this study, researchers developed an acellular bioscaffold made from ovine tendon collagen with an antibacterial coating for treating skin wounds. They found that genipin crosslinking improves the scaffold's properties, and with plasma polymerisation, it enhances antibacterial activity, potentially benefiting wound healing.
2 citations
,
February 2024 in “Pharmaceutics” This review highlights that while chitosan-based wound dressings with silver nanoparticles show promise for treating infected wounds due to enhanced antimicrobial activity, further studies are needed to address their in vivo toxicity and evaluate their efficacy in infectious animal models.
2 citations
,
August 2020 in “International Journal of Cosmetic Science” This study suggests that Lindera strychnifolia root extract may help restore a healthy microbial balance on the scalp in men with androgenetic alopecia after 83 days of treatment.