July 2022 in “medRxiv (Cold Spring Harbor Laboratory)” This review supports an autoimmune hypothesis for Satoyoshi syndrome, noting associations with autoantibodies and autoimmune diseases, and reports an observed improvement in most patients with corticosteroid or immunosuppressant treatments.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that TGM2 appears to play a crucial role in sebocyte differentiation and may act as a negative regulator of lipid metabolism in sebaceous glands.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that tissue transglutaminase (TG2) may play a role in sebum production by regulating autophagy in sebaceous glands, offering potential targets for dermatological interventions.
17 citations
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April 2013 in “Experimental and Therapeutic Medicine” This study found that anti-Sjögren's syndrome type B antibodies are highly specific for diagnosing systemic lupus erythematosus and are associated with several clinical symptoms, including cheek erythema and alopecia.
66 citations
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March 2016 in “Nucleic Acids Research” This study found that Musashi-2 regulates mRNA targets to restrict epithelial cell migration, revealing a key function of Msi2 beyond its known role in promoting cell growth.
16 citations
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September 2006 in “The Journal of Immunology” This study identified that mouse MILL1 and MILL2 are glycoproteins distinct from human MICA/B, primarily due to their association with β2-microglobulin and TAP-independent surface expression.
This study found that using SH-SY5Y cell lysate in Western blot analysis may improve the diagnosis of Satoyoshi syndrome by providing more consistent and clear immunoreactive band patterns compared to brain homogenate, potentially leading to earlier diagnosis and treatment.
14 citations
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July 2015 in “International Journal of Molecular Sciences” This study found that S-Methylmethionine sulfonium (SMMS) enhances cell survival and reduces damage from UVB irradiation in skin cells, suggesting its potential as a cosmetic ingredient for UV protection.
1 citations
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February 1991 in “Journal of Biological Chemistry” 9 citations
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September 1989 in “PubMed” This study observed that selenium levels were lower in Sudanese children with malnutrition compared to healthy German children, with a good correlation between selenium and glutathione peroxidase activity.
13 citations
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March 1999 in “Biochemical Journal” In this study, transgenic mice overexpressing the SSAT gene were highly sensitive to polyamine analogues, leading to severe liver changes and high mortality rates after treatment.
6 citations
,
May 1986 in “Cancer Chemotherapy and Pharmacology” The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.
July 2024 in “International Journal of Molecular Sciences” This article proposes using the hallmarks of ageing and dysregulated microRNAs to create a molecular morbidity score that could improve prognostication and clinical trial inclusion for patients with multimorbidity.
March 2005 in “Journal of the American Academy of Dermatology” Recognizing minor skin lesions can help identify serious cancer syndromes.
12 citations
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July 2015 in “Tissue Antigens” In this study, the AA genotype of C2 polymorphism was more frequently observed in Chinese patients with systemic lupus erythematosus than controls, indicating it may be a risk factor for the disease.
5 citations
,
October 2021 in “American Journal of Medical Genetics Part A” This case report identifies a novel maternally inherited MBTPS2 variant associated with an expanded phenotypic spectrum of BRESHECK syndrome, including cytopenias, bone marrow fibrosis, and chronic diarrhea.
This study found that four bacterial isolates from a microbiology laboratory collection demonstrated resistance to selenate, with molecular analysis showing they closely resemble different strains of Bacillus megaterium.
43 citations
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February 1999 in “Biochemical Journal” This study found that transgenic mice overexpressing the SSAT gene under a metallothionein promoter suffered delayed hair loss and were highly sensitive to polyamine analogues, which led to significant liver changes and mortality.
This study reports that a specific transporter protein in Staphylococcus hominis is responsible for transporting a malodour precursor, thereby playing a key role in human body odor production.
126 citations
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November 1987 in “The Journal of Pediatrics” This study reports that selenium deficiency in children on long-term total parenteral nutrition may lead to symptoms like erythrocyte macrocytosis and skin and hair depigmentation, which improved with selenium supplementation.
January 1987 in “Toxicological sciences” In this study, SMR-2 and SMR-6, retinoid analogs, were found to be approximately 100 times more toxic than retinoic acid in male mice, primarily affecting skin, immune, and reproductive systems.
37 citations
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September 2003 in “Journal of Medicinal Chemistry” This study found that compound 2g inhibits steroid sulfatase effectively without exhibiting estrogenic activity, making it a promising candidate for breast cancer treatment.
April 2024 in “The Journal of urology/The journal of urology” In this study, researchers found that methylation of the SRD5A2 gene in blood and tissue samples can serve as a biomarker to predict men's clinical response to finasteride treatment for benign prostatic hyperplasia, offering a non-invasive method for assessing potential treatment success.
115 citations
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December 1996 in “PubMed” This study observed that the intestinal absorption of selenium varies depending on its chemical form, with selenomethionine being absorbed efficiently and selenium as selenodiglutathione or selenodicysteine being absorbed faster than selenite.
50 citations
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September 2023 in “Biomarker Research” This review focuses on S100A6, a Ca²⁺-binding protein, detailing its role in cell functions, the regulation of its expression, and its potential as a biomarker and therapeutic target in various diseases.
29 citations
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September 1990 in “Biochemical Journal” This study reports the purification of a specific sulphotransferase from rat liver that catalyzes the sulphation of minoxidil, potentially implicating it in minoxidil's bioactivation.
25 citations
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January 2012 in “Proteome Science” This study suggests that common proteomic changes, including the expression of the protein S100A6, may occur during the expansion of AD-MSC from different donors.
15 citations
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May 1987 in “Fundamental and applied toxicology” This study found that SMR-2 and SMR-6, analogs of retinoic acid and retinol, were approximately 100 times more toxic than retinoic acid in mice, inducing hypervitaminosis A and affecting various organs and tissues.
2 citations
,
June 2004 in “Journal of Molecular Histology”
39 citations
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July 2013 in “Journal of dermatological science” This study found that microRNA levels in hair shafts were significantly decreased in scleroderma patients compared to normal subjects, suggesting they may serve as effective biomarkers.