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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

MC4R gene variants not linked to female hair loss.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.

Genes and hormones cause hair loss, with four genes contributing equally.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Two gene variations, rs6493497 and rs7176005, may be linked to female hair loss in Chinese people.

Glioblastoma cells can make androgens, which might help the tumor grow.

The document concludes that hair loss is influenced by genetics and other factors, and while treatments like finasteride can help, they have limitations and side effects.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

The conclusion is that more research is needed to understand if the drug finasteride causes Post-Finasteride Syndrome or if it's due to individual genetic makeup.