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Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Post-finasteride syndrome's existence is uncertain; more research needed.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Modern research supports traditional uses of Yarrow for hair loss and skin issues.

Methylation in specific gene region causes finasteride resistance in some BPH patients.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

PGD2 stops hair growth and is higher in bald men with AGA.

Hair loss needs more research for better treatments.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.