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    Research 31–60 of 437

    1. DNMT1 targets SRD5A2 to induce mitochondrial homeostasis and EMT in urothelial cells of hypospadias Molecular Biology Reports · 2025
    2. MP09-17 METHYLATION OF SRD5A2 IN THE BLOOD AS A NOVEL BIOMARKER TO PREDICT SENSITIVITY TO 5-ARI TREATMENT 2024
    3. Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism bioRxiv (Cold Spring Harbor Laboratory) · 2020
    4. SRD5A2 and emerging therapies in androgen-driven disorders Nature Reviews Urology · 2026
    5. Cloning, computational analysis and expression profiling of steroid 5 alpha-reductase 1 (SRD5A1) gene during reproductive phases and ovatide stimulation in endangered catfish, Clarias magur Scientific reports · 2023
    6. PD02-05 SRD5A2 EXPRESSION IS A PREDICTOR OF RESPONSE TO FINASTERIDE IN THE MTOPS TRIAL The Journal of Urology · 2023
    7. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach Journal of Herbal Medicine · 2022
    8. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach Research Square (Research Square) · 2022
    9. Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes Journal of Investigative Dermatology · 1998 · 169 citations
    10. Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors Birth Defects Research · 2003 · 103 citations
    11. Steroidogenesis of the testis – new genes and pathways Annales d'endocrinologie · 2014 · 70 citations
    12. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 57 citations
    13. 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes Endocrinology · 2015 · 54 citations
    14. The slick hair coat locus maps to chromosome 20 in Senepol-derived cattle Animal Genetics · 2007 · 51 citations
    15. Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy Biomaterials · 2019 · 47 citations
    16. 5α-Reduced glucocorticoids: a story of natural selection Journal of Endocrinology · 2011 · 46 citations
    17. Sex dependent influence of a functional polymorphism in steroid 5‐α‐reductase type 2 (<i>SRD5A2</i>) on post‐traumatic stress symptoms American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2013 · 35 citations
    18. Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride Nature Communications · 2020 · 30 citations
    19. Rare and common genetic determinants of metabolic individuality and their effects on human health Nature Medicine · 2022 · 29 citations
    20. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    21. Effect of <i>Ficus carica</i> leaf extract on the gene expression of selected factors in HaCaT cells Journal of Cosmetic Dermatology · 2017 · 16 citations
    22. Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression Biological & Pharmaceutical Bulletin · 2016 · 15 citations
    23. Subcellular localization of the five members of the human steroid 5α-reductase family Biochimie open · 2017 · 13 citations
    24. Worldwide cohort study of 46, XY differences/disorders of sex development genetic diagnoses: geographic and ethnic differences in variants Frontiers in Genetics · 2024 · 13 citations
    25. Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract Plants · 2022 · 9 citations
    26. Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities Plants · 2022 · 7 citations
    27. Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing Journal of Nanobiotechnology · 2022 · 7 citations
    28. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 7 citations
    29. Upregulation of mir-1199-5p is associated with reduced type 2 5-α reductase expression in benign prostatic hyperplasia BMC Urology · 2022 · 6 citations
    30. Evolution, classification, structure, and functional diversification of steroid 5α-reductase family in eukaryotes Heliyon · 2024 · 6 citations