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Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

Higher DHT in male baldness may protect against prostate cancer.

MC4R gene variants not linked to female hair loss.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Androgens can both increase body hair and cause scalp hair loss.

The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.

Finasteride helps reduce heart enlargement in heart failure patients.

AGA in children needs careful diagnosis due to low androgen levels and possible other causes.

Researchers found a new ABCD1 gene mutation linked to a rare brain and nerve disorder with unusual brain changes.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Two gene variations, rs6493497 and rs7176005, may be linked to female hair loss in Chinese people.

Prenatally androgenized ewes can model increased hair diameter in women with PCOS.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Glioblastoma cells can make androgens, which might help the tumor grow.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

ESR2 gene linked to female-pattern hair loss.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Certain gene variations increase male hair loss risk, influenced by hormone levels.

Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

The document concludes that hair loss is influenced by genetics and other factors, and while treatments like finasteride can help, they have limitations and side effects.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.