research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
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research Targeting the Hippo/YAP/TAZ Signalling Pathway: Novel Opportunities for Therapeutic Interventions into Skin Cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Special Collection on Inward Rectifying Potassium Channels
Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein 1 and Desmoglein 3: A Tool Representing All Pemphigus Variants
New mouse models of Pemphigus show severe symptoms and need better treatments.
research Vitamin D Metabolism and Function in the Skin
Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
research Clinical Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology
Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.
research Pharmacology of Anabolic Steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Chemotherapy-Induced Alopecia
Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
research Fibroproliferative Genes Are Preferentially Expressed in Central Centrifugal Cicatricial Alopecia
Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
research Is COVID-19 a Risk Factor for Progression of Benign Prostatic Hyperplasia and Exacerbation of Its Related Symptoms?: A Systematic Review
COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
research Hypothalamic DNA Methylation in Rats with Dihydrotestosterone-Induced Polycystic Ovary Syndrome: Effects of Low-Frequency Electro-Acupuncture
Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
research Adverse Hair Reactions to New Targeted Therapies for Cancer
New cancer treatments are less harmful to hair but can still cause hair loss, color, shape, and growth changes.
research Effects of Baicalin on Alopecia and the Associated Mechanism
Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.
research Protein Kinase C Is a Key Target for Attenuation of Leigh Syndrome by Rapamycin
Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
research Novel Janus Kinase Inhibitors in the Treatment of Dermatologic Conditions
JAK inhibitors show promise for treating various skin diseases.
research Cutaneous Reactions to Chemotherapeutic Drugs and Targeted Therapy for Cancer
Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Metformin And Malignant Neoplasms: A Possible Mechanism Of Antitumor Action And Prospects For Use In Practice
Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.
research Unexpected Autocrine Role of Vascular Endothelial Growth Factor in Squamous Cell Carcinoma
VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.
research CXXC5: A Novel Regulator and Coordinator of TGF-β, BMP, and Wnt Signaling
CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
research Nilotinib-Induced Keratosis Pilaris
Nilotinib can cause keratosis pilaris, a skin condition.
research Botryococcus Terribilis Ethanol Extract Exerts Anti-Inflammatory Effects on Murine RAW264 Cells
Botryococcus terribilis Ethanol Extract may reduce inflammation by changing gene expression in cells.
research Myristoleic Acid Promotes Anagen Signaling by Autophagy Through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells
Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.
research In Vitro and In Vivo Models for the Development of Hair Growth Materials by Regulating the β-Catenin Signaling Pathways
The research found a way to develop hair growth materials by targeting a specific signaling pathway.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research Woolly Antics Between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research Interaction Between Stem Cell Factor and Endothelin-1: Effects on Melanogenesis in Human Skin Xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.