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Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Cyclosporin A promotes hair growth in mice and increases a protein linked to hair growth, but it may not work the same way in humans.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.

COVID-19 can cause different skin issues, including rashes and hair loss.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Multi-pass laser skin treatments improved healing, reduced pain, and had no major complications.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Estrogen therapy can reduce skin aging but has cancer risks.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.