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The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

HPV8 causes hair follicle stem cells to grow, leading to skin lesions.

HPV8 E6 gene causes growth of certain skin stem cells.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

NGAL indicates abnormal skin cell differentiation.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.

A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Notch signalling helps skin cells differentiate and prevents tumors.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Dabrafenib can cause skin growths and sometimes low-grade skin cancer.

Voriconazole can cause serious side effects, especially in long-term use.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

The term "porokeratotic adnexal ostial nevus" is proposed to unify overlapping skin conditions involving eccrine and hair follicles.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

BRAF inhibitors for melanoma often cause skin side effects, but they can be managed with proper care.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Erosive pustular dermatosis of the scalp is a type of skin inflammation often confused with other conditions, requiring continuous treatment.

New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.