research Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
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research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Metformin And Malignant Neoplasms: A Possible Mechanism Of Antitumor Action And Prospects For Use In Practice
Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.
research The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis
Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.
research Posters Presented at the 19th Joint Meeting of the International Society of Dermatopathology, March 2–3, 2016, Hilton Crystal City at Washington Reagan National Airport, Arlington, Virginia, USA
The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Cutaneous Adverse Effects of Targeted Therapies
Targeted cancer therapies often cause serious skin problems that need careful management.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Liposomes in Cosmeceuticals
Liposomes could improve how skin care products work but are costly and not very stable.
research Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Keratin 79 Identifies a Novel Population of Migratory Epithelial Cells That Initiates Hair Canal Morphogenesis and Regeneration
Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research TGFβ and Cancer Metastasis: An Inflammation Link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Ginseng Phytochemicals as Therapeutics in Oncology: Recent Perspectives
Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
research Eupafolin Nanoparticles Protect HaCaT Keratinocytes from Particulate Matter-Induced Inflammation and Oxidative Stress
Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
research Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer
Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
research Oncogenic Senescence: A Multi-Functional Perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
research Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections
Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-Epithelialization
Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
research Stem Cells and the Skin
Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
research Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine
Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
research Next-Generation Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Pleomorphic Appearance of Breast Cancer Cutaneous Metastases
Breast cancer skin metastases are rare, look different, and can be confused with other skin issues, so a biopsy is needed for accurate diagnosis.
research Polycomb Repressive Complex 2 in Adult Hair Follicle Stem Cells Is Dispensable for Hair Regeneration
Polycomb Repressive Complex 2 is not needed for hair regeneration.
research Indian Gooseberry (Emblica Officinalis Gaertn.) Pharmacological Properties
Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
research Interventional and Intrinsic Airway Homeostasis and Repair
The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.