50 citations
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September 2012 in “Developmental Biology” This study found that over-expressing Spry4 and Fgf10 modulates feather stem cells to alter feather morphologies in distinct ways, affecting barb branch formation and tissue structure.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
April 2023 in “Journal of Investigative Dermatology” In this study, it was found that the PSR™ technology enhanced the phytochemical content and antioxidant and anti-aging properties of sprouted seed extracts compared to conventional methods, with growth temperature also affecting the extract's composition and quality.
2 citations
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November 2019 in “Phytotherapy Research” This study found that consuming 100 mg of pea sprout extract daily for 8 weeks significantly reduced hair loss in individuals experiencing excessive hair shedding.
1 citations
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January 2013 in “Asian Journal of Beauty and Cosmetology” This study found that wheat sprout extract promoted hair growth in female C57BL/6 mice, suggesting its potential application in hair remedy products.
June 2026 in “Lahore Garrison University Journal of Life Sciences” In this preliminary study, selenium-resistant bacteria and selenium-treated pea sprout extracts showed minimal inhibitory effects on the dandruff-associated fungus Malassezia furfur compared to controls, suggesting potential for further investigation.
January 2026 in “Environmental Science and Pollution Research” In this study, oral administration of wheat sprout extract significantly protected rats against skin damage caused by acrylamide exposure by enhancing antioxidant defenses, reducing oxidative stress, and preserving skin structure, highlighting its potential as a sustainable protective agent against environmental skin toxins.
November 2025 in “Journal of Microbiology and Biotechnology” This study demonstrates that pea sprout extract promotes hair growth by activating specific signaling pathways and providing antioxidant and anti-inflammatory effects, suggesting its potential as a natural alopecia treatment.
August 2025 in “International Journal of Molecular Sciences” This study found that sulforaphane-rich broccoli sprout extract significantly accelerated hair regrowth in a mouse model of androgenetic alopecia, suggesting its potential as a safe and effective natural therapy.
January 2018 in “Journal of translational science” In this study, oral broccoli sprouts intake did not affect plasma androgen levels in males, while alfalfa sprouts intake increased testosterone and DHT levels, which may help prevent male late onset hypogonadism.
June 2017 in “Yakakoeji/Yaghag hoeji” This study found that Wheat Sprout MeOH extract increased cell proliferation in human hair dermal papilla cells through the activation of ERK and Akt signaling pathways.
115 citations
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October 2003 in “Journal of Neuroscience” This study found no evidence supporting the hypothesis that Aβ afferents sprout into the superficial laminas of the spinal cord after nerve injury in rats.
April 2026 in “Antioxidants” In this study, broccoli sprout extract and sulforaphane were found to reduce cell viability, suppress growth, and induce apoptosis in breast cancer cells, and oral broccoli sprout extract inhibited tumor growth in animal models, suggesting it may be effective in managing breast cancer.
February 2024 in “Scientific Reports” In this study, cinnamic acid was found to enhance hair growth in human dermal papilla cells and hair follicle organoids by activating oxytocin signaling, suggesting its potential for developing hair growth-promoting products.
April 2012 in “한국생물공학회 학술대회”
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study on adult-onset, whole body Spry1/2/4 triple knockout mice, researchers observed endocrine abnormalities and no increased tumor incidence, despite similar food intake and motor function.
June 2026 in “Scientific Reports” This study identified hypericin and berberine as compounds that can support hair growth by enhancing oxytocin receptor expression and acting as an oxytocin receptor agonist, respectively, potentially serving as practical alternatives to oxytocin for treating hair-loss diseases.
1 citations
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September 2025 in “Physiologia” This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.
3 citations
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January 2023 in “Journal of Hunan University Natural Sciences” In this study, researchers developed a natural shampoo using traditional plant extracts and reported that its physicochemical properties and antioxidant activity were comparable to marketed shampoos. Further research is needed to confirm its performance and quality.
184 citations
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October 2007 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.
43 citations
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April 2021 in “Angiogenesis” This review examines the evolving understanding of lymphatic vessel development, emphasizing new cellular mechanisms and lineage diversity, while discussing experimental methods and identifying key knowledge gaps.
21 citations
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April 2021 in “Biofabrication” This study developed a vascularized full-thickness skin equivalent with a complex vascular network, enhancing its predictiveness for topical and systemic drug applications in dermatology research.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
July 2024 in “Journal of Investigative Dermatology” Topical sulforaphane reduces pigmentation and wrinkles from sun damage.
October 2023 in “Scientific Reports” This study explored the effects of oxytocin on hair growth and found that it upregulated growth-promoting factors in dermal papilla cells and hair follicle organoids, suggesting potential for developing new alopecia treatments.
June 2021 in “International Journal of Pharma and Bio Sciences” This study found that a wheat-protein based herbal shampoo with natural ingredients demonstrated good conditioning performance, cleansing properties, and surface tension, helping to clear dirt, dandruff, and promote hair strength and darkness without causing hair damage, but further work is needed to enhance its quality.
December 2013 in “대한피부미용학회지” In this study, wheat sprout extract (fr. 5) application was associated with increased hair growth in C57BL/6 mice, suggesting its potential as a hair remedy product.
24 citations
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January 2007 in “The FASEB Journal” This study developed a rat model for catamenial epilepsy, suggesting that neurosteroid withdrawal may increase seizure frequency and help test new treatments.
13 citations
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November 2017 in “Neurotoxicity research/Neurotoxicity resarch” This study found that sodium metabisulfite activates sodium channels and increases cellular excitability and excitotoxicity in both cardiomyocyte and neuron models, which exacerbates seizures and neuronal damage in rats.
May 2025 in “Neuropharmacology” This study in neonatal rats found that inhibiting neurosteroid synthesis with finasteride unexpectedly reduced the severity and duration of neonatal seizures following birth asphyxia, maintained cognitive functions, but increased anxiety-like behaviors, highlighting a complex role of neurosteroids in hypoxic-ischemic encephalopathy outcomes.