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The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.

Almost half of COVID-19 patients in Makkah, Saudi Arabia experienced increased hair loss, especially women and those with chronic diseases.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

A woman with EMS showed unusual skin mucinosis without the typical hard skin syndrome, suggesting EMS can cause skin mucinosis.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Combining microdermabrasion with steroid injections improves hair regrowth in scalp alopecia areata.

Visual field defects in lupus nephritis can be caused by hypertensive retinopathy, not glaucoma or medication toxicity.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.

Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

CD80CD86 deficiency causes hair loss by disrupting regulatory T cells.

Experts say proper treatment and sensitivity are important for women's facial skin issues like acne and unwanted hair.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

AGEs may cause hair loss by increasing inflammation in hair follicles.

Some treatments for autoimmune hair loss work, but JAK inhibitors like tofacitinib are promising for regrowth.

The document says that hookworms are treated with mebendazole and stress-related hair loss usually gets better in 6 months, while other hair loss types have specific treatments.

A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.

A high-fat diet may weaken tongue structure by reducing certain protein genes.