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Dextran sulfate was found to be toxic and ineffective for treating HIV.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Finasteride effectively blocks enzyme causing male pattern baldness.

Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

TSH is usually the only test needed to check thyroid function in primary care.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

Methotrexate reduced the need for steroids in asthma patients without worsening their condition.

Created material boosts hair growth and kills bacteria for wound healing.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Imiquimod 5% cream reduced equine sarcoids in most cases.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Oral dutasteride and topical pimecrolimus can safely and effectively treat Frontal Fibrosing Alopecia, leading to significant hair regrowth.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.