April 2023 in “Australasian Journal of Dermatology” Both methods of platelet-rich plasma showed positive effects on hair loss.
June 2024 in “Archives of dermatological research” In this self-controlled comparative study of 16 women with Female Pattern Hair Loss, MMP® with Minoxidil showed a better response in the parietal-vertex regions in less advanced cases compared to standard Minoxidil treatment, though overall effectiveness was similar.
1 citations
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October 2021 in “QJM: An International Journal of Medicine” This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.
25 citations
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June 2018 in “Clinical and Experimental Dermatology” This study found that combining fractional radiofrequency microneedling with 5% topical minoxidil improved hair count and thickness more than minoxidil alone in Chinese men with male pattern hair loss.
1 citations
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February 2021 This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.
July 2022 in “British Journal of Dermatology” July 2022 in “British Journal of Dermatology”
5 citations
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July 2020 in “Journal of Cosmetic Dermatology” This study found that using a vibration anesthetic device during scalp mesotherapy significantly reduced pain in patients with androgenetic alopecia and alopecia areata compared to the non-vibration side.
November 2015 in “Hair transplant forum international” PRP may help with hair regrowth in male pattern baldness, but more research is needed.
September 2025 in “Journal of Maxillofacial and Oral Surgery” This study found that combining PRP with concentrated growth factors was more effective than PRP alone in promoting hair regrowth for patients with androgenetic alopecia.
January 2020 in “Global dermatology” This study found that iontophoresis with growth factor cocktail including fibroblast growth factor 5-short significantly increased hair density in patients with androgenetic alopecia over 24 weeks.
2 citations
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August 2021 in “Photodiagnosis and Photodynamic Therapy” In this study, 5-aminolevulinic acid photodynamic therapy did not improve hair growth in patients with androgenetic alopecia but was safe and slightly reduced scalp sebum secretion.
7 citations
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January 2017 in “International Journal of Dermatology” This study found that superficial cryotherapy significantly increased hair density and thickness in treated eyebrows compared to untreated controls after 5 months in patients with alopecia areata.
January 2021 in “Global Dermatology” This study involved selecting patients with specific types of alopecia for treatment but does not report clinical outcomes.
29 citations
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April 2019 in “Lasers in Medical Science” This study found that combining fractional erbium-glass laser therapy with topical minoxidil significantly improved hair density and diameter in men with androgenetic alopecia compared to using minoxidil alone over a 24-week period, with no serious adverse events reported.
21 citations
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January 2018 in “Lasers in Medical Science” This study concluded that 12 sessions of fractionated thulium laser treatment improved hair density and thickness in patients with pattern hair loss, with further benefits from adding a growth factor solution post-treatment.
January 2020 in “프로그램북(구 초록집)” This study found that treating androgenetic alopecia patients with microneedle-delivered GFC containing FGF5s and NMN increased hair density and diameter compared to normal saline.
January 2016 in “International archives of medicine” In this study, a significant relationship was observed between hair coloring and both hair damage and scalp problems among students at the University of Sumatera Utara.
7 citations
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September 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” In this randomized controlled trial, occipital donor sites for split-thickness skin grafts showed superior re-epithelialization, reduced pain, fewer complications, and better cosmetic outcomes compared to femoral donor sites.
4 citations
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June 2024 in “Journal of Cosmetic Dermatology” In this study, fractional radiofrequency treatment was found to be effective, safe, and well-tolerated for patients with erythematotelangiectatic rosacea, with high satisfaction rates.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that adipose stem cell exosomes, combined with microneedling, improved facial skin wrinkles, elasticity, hydration, and pigmentation compared to a placebo, with significant results on the Global Aesthetic Improvement Scale and no serious adverse events noted in treated individuals.
2 citations
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December 2024 in “JPRAS Open” In this study, patients experienced scarless regenerative healing of scalp donor wounds, and the researchers highlighted that proper wound dressing can prevent alopecia and scarring in infected wounds, suggesting the potential of scalp skin grafts for optimal healing.
January 2022 in “Journal of Cosmetic Dermatology” This study found that placebo groups in split-scalp PRP trials for androgenetic alopecia showed less hair loss compared to whole-head trial placebo groups, likely due to PRP diffusion in split-scalp designs.
2 citations
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September 2023 in “Journal of clinical medicine” This study found that using autologous ultra-thin split-thickness skin grafts from the scalp with the DermaBlade tool led to rapid wound healing, minimal complications, and improved cosmetic outcomes for 90% of patients with lower extremity lesions, without causing scarring or alopecia.
November 2025 in “Mendeley Data” This study outlines a randomized trial investigating the effects of botulinum toxin administered before hair transplantation to potentially improve outcomes by enhancing blood flow and reducing graft failure due to ischemia in androgenetic alopecia patients.
June 2024 in “Dermatology and therapy” This study reviewed recent advancements in using botulinum toxin for treating androgenetic alopecia and emphasized the need for further research to determine the most effective injection sites and depths, as current strategies show inconsistent results.
January 2026 in “Journal of Cosmetic Dermatology” In this 10-patient exploratory study, the researchers found that topical application of 4-aminopyridine 5% combined with microneedling did not improve hair density or quality in men with androgenetic alopecia, suggesting limited efficacy in this context despite promising results in animal wound models.
November 2025 in “Mendeley Data” This study outlines a randomized trial to assess if administering botulinum toxin before hair transplantation can improve outcomes by enhancing blood flow and reducing ischemia-induced graft failure in patients with androgenetic alopecia.
November 2025 in “Mendeley Data” This study explores the hypothesis that preoperative administration of botulinum toxin could enhance hair transplantation outcomes by improving scalp microenvironment and reducing ischemia-induced graft failure, using a randomized split-scalp controlled trial design.
18 citations
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September 2006 in “Dermatologic Surgery” This study reported that squamous cell carcinomas of the scalp can become extraordinarily aggressive, highlighting the need for early diagnosis and careful use of treatment strategies like wide excision and radiation therapy.