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120-150 / 1000+ resultsresearch Dermoscopic Evaluation of the Efficacy of Combination of Topical Spironolactone 5% and Minoxidil 5% Solutions in the Treatment of Androgenetic Alopecia, Comparative Study
research Retrospective Study of the Prevalence of Hyperkalemia in Women Taking Spironolactone for Acne, Hair Loss, and Hirsutism
research Retrospective Study of the Prevalence of Hyperkalemia in Women Taking Spironolactone for Acne, Hair Loss, and Hirsutism
research Increased Risk of Hyperkalemia in Older Women Taking Spironolactone for Female Pattern Hair Loss
research A Review of the Efficacy and Safety Profile of Oral Spironolactone Use for Androgenic Alopecia
research A Randomized Trial of 5% Minoxidil Versus Combination of 5% Minoxidil and Oral Spironolactone in Treatment of Female Pattern Hair Loss
research Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator-Blinded, Randomized Trial
research Retrospective Analysis of the Risk of Hyperkalemia in Women Older Than 65 Years of Age Prescribed Spironolactone for Female-Pattern Hair Loss
![Bioavailability of Albumin-Bound Testosterone](/images/research/89865285-5c32-44b7-89cb-31e806e2aff9/small/21212.jpg)
research Bioavailability of Albumin-Bound Testosterone
Spironolactone treatment increases the amount of testosterone available in the body.
![A Systematic Review of Commonly Used Medical Treatments for Hirsutism in Women](/images/research/b72d6465-f3ec-49e4-9947-f597c4a3237c/small/27558.jpg)
research A Systematic Review of Commonly Used Medical Treatments for Hirsutism in Women
Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.
![New Therapeutic Approach to the Hirsute Patient](/images/research/07c5cf2b-4fb8-458f-842b-1b3ad84dab7f/small/34474.jpg)
research New Therapeutic Approach to the Hirsute Patient
Spironolactone can reduce hair growth in women with hirsutism.
![Anti-Androgens May Protect Against Severe COVID-19 Outcomes: Results From a Prospective Cohort Study of 77 Hospitalized Men](/images/research/c438745b-bbd0-43a1-9c85-aab09f39b505/small/11541.jpg)
research Anti-Androgens May Protect Against Severe COVID-19 Outcomes: Results From a Prospective Cohort Study of 77 Hospitalized Men
Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.
![Hirsutism: Evaluation and Treatment](/images/research/b4eb2bfa-5021-4809-817f-97d5fc8fd3d7/small/34464.jpg)
research Hirsutism: Evaluation and Treatment
Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
![A Review of Hormone-Based Therapies to Treat Adult Acne Vulgaris in Women](/images/research/83acb81f-56b6-4974-bc6b-2022073433dd/small/18288.jpg)
research A Review of Hormone-Based Therapies to Treat Adult Acne Vulgaris in Women
Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.
![Anti-Androgen Treatments for Hirsutism and Acne in Women of Childbearing Age](/images/research/d72e948d-0741-407c-9bb5-814f1718c758/small/28080.jpg)
research Anti-Androgen Treatments for Hirsutism and Acne in Women of Childbearing Age
For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.
![Scalp Hair Regrowth in Hormone-Treated Transgender Woman](/images/research/82b21d4c-f538-4ba7-9850-833b9583fc68/small/18556.jpg)
research Scalp Hair Regrowth in Hormone-Treated Transgender Woman
Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.
![Treatment of Androgenic Disorders in Women: Acne, Hirsutism, and Alopecia](/images/research/99a55974-cc27-410b-97e6-9925d5e6e6a8/small/27691.jpg)
research Treatment of Androgenic Disorders in Women: Acne, Hirsutism, and Alopecia
Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.
![A Review of Hormonal Therapy for Female Pattern (Androgenic) Alopecia](/images/research/e239fd36-b289-40c3-9c47-df2a4b63a437/small/12313.jpg)
research A Review of Hormonal Therapy for Female Pattern (Androgenic) Alopecia
Hormonal therapies like cyproterone acetate and spironolactone may help some women with hair loss, but finasteride 1mg is not useful, and the effectiveness of other treatments is still unclear.
![Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome](/images/research/23277e4d-48e4-419a-b7b5-127102e297ea/small/13625.jpg)
research Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome
Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
![Other Antiandrogens: Alternative Treatments for Acne and Hirsutism](/images/research/dd2199be-50d1-4bf5-b2ca-1620abc88d2a/small/27656.jpg)
research Other Antiandrogens: Alternative Treatments for Acne and Hirsutism
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
![An Inherited Nail Dystrophy Principally Affecting the Great Toenails](/images/research/0ab25cb4-75a5-4b73-9466-a3e6784ff028/small/21220.jpg)
research An Inherited Nail Dystrophy Principally Affecting the Great Toenails
The document concludes that an inherited nail condition often improves on its own, and spironolactone effectively treats acne in women.
![Use of Spironolactone in Dermatology: Acne, Hidradenitis Suppurativa, Female Pattern Hair Loss, and Hirsutism](/images/research/a7467ae2-77b8-41af-bafa-0c15d92b1d95/small/17394.jpg)
research Use of Spironolactone in Dermatology: Acne, Hidradenitis Suppurativa, Female Pattern Hair Loss, and Hirsutism
Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
![Becker’s Nevus Syndrome in a Pediatric Female Patient](/images/research/0d79e86b-b965-4b3c-927a-d2be00c3fe25/small/32610.jpg)
research Becker’s Nevus Syndrome in a Pediatric Female Patient
A girl with Becker's nevus syndrome showed good improvement in breast development using spironolactone.
![An Open-Label Prospective Observational Study of Antiandrogen and Non-Antiandrogen Early Pharmacological Approaches in Females with Mild-to-Moderate COVID-19: The Pre-AndroCoV Female Trial](/images/research/49e824a4-ed48-43b9-8a73-01fc33628cbb/small/17386.jpg)
research An Open-Label Prospective Observational Study of Antiandrogen and Non-Antiandrogen Early Pharmacological Approaches in Females with Mild-to-Moderate COVID-19: The Pre-AndroCoV Female Trial
Early treatment improved COVID-19 outcomes, and spironolactone helped reduce risks in females with high androgen levels.
![Acquired Uncombable Hair Syndrome in a 39-Year-Old Woman](/images/research/74013401-b271-4387-9ead-f81cae883c67/small/21096.jpg)
research Acquired Uncombable Hair Syndrome in a 39-Year-Old Woman
A woman's hair changed to a dry, tangled texture that's hard to comb after treatment with spironolactone, suggesting the medication might cause such hair changes.
![Drug-Induced Gynecomastia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials](/images/research/61c8632c-5fbd-4d4e-b75a-c3910a9c6ea7/small/31760.jpg)
research Drug-Induced Gynecomastia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.
![Concurrence of Giant Cell Arteritis in a Patient with De Quervain's Thyroiditis](/images/research/dbde9c16-cde3-4500-9889-0fd0926fbf58/small/15606.jpg)
research Concurrence of Giant Cell Arteritis in a Patient with De Quervain's Thyroiditis
Spironolactone may help reduce hair loss in androgenic alopecia.
![Androgenetic Alopecia: Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society](/images/research/f830cdd0-e10b-4994-aec6-909a3be60b0c/small/4194.jpg)
research Androgenetic Alopecia: Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society
Use trichoscopy to diagnose hair loss; treat with minoxidil, finasteride, or dutasteride; consider platelet-rich plasma and spironolactone.
![Drug Repurposing in Dermatology: Molecular Biology and Omics Approach](/images/research/e00e0d1c-c66e-4254-ba9c-16d29af82ef8/small/13276.jpg)
research Drug Repurposing in Dermatology: Molecular Biology and Omics Approach
Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.