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Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Skin RAGE levels are linked to inflammation and cell death.

A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.

The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Understanding skin structure and development helps diagnose and treat skin disorders.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Keratins are important for skin cell health and their problems can cause diseases.

Mice with human skin protein K8 had more skin problems and cancer.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Vitamin D and calcium are important for quick and effective skin wound healing.

Symmetrical Acrokeratoderma (SAK) may be a unique skin condition in China, lacking specific treatment and needing long-term monitoring.

A specific group of skin stem cells was found to help maintain hair follicle cells.