research Reduced SMAD2/3 Activation Independently Predicts Increased Depth of Human Cutaneous Squamous Cell Carcinoma
Lower SMAD2/3 activation predicts more severe skin cancer.
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research A Systematic Review of Keratinocyte Secretions: A Regenerative Perspective
Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
research MAD2B Acts as a Negative Regulatory Partner of TCF4 on Proliferation in Human Dermal Papilla Cells
MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Targeting the Hippo/YAP/TAZ Signalling Pathway: Novel Opportunities for Therapeutic Interventions into Skin Cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro
A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.
research Plasma-Polymerized Antibacterial Coating of Ovine Tendon Collagen Type I Crosslinked with Genipin and Dehydrothermal-Crosslinked as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair Follicle Neogenesis
The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
research Comparative Characterization and Osteogenic/Adipogenic Differentiation of Mesenchymal Stem Cells Derived from Male Rat Hair Follicles and Bone Marrow
Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.
research Role of Regeneration in Tissue Repairing and Therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Nanomaterials in Hair Care and Treatment
Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.
research The Mechanisms and Functions of Interorganelle Interactions
Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.
research Menopausal Androgen Excess-Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumor (Case Report and Mini-Review of Literature)
High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
research Disease Prevention and Alleviation by Human Myoblast Transplantation
Myoblast transplantation shows promise for treating various muscle and heart conditions.
research Zinc and Zinc Transporters in Dermatology
Zinc is crucial for skin health and treating various skin disorders.
research SCD1 Sustains Homeostasis of Bulge Niche via Maintaining Hemidesmosomes in Basal Keratinocytes
SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.
research From Hair to Liver: Emerging Application of Hair Follicle Mesenchymal Stem Cell Transplantation Reverses Liver Cirrhosis by Blocking the TGF-β/Smad Signaling Pathway to Inhibit Pathological HSC Activation
Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.
research TMT-Based Quantitative Proteomic Analysis Reveals the Effect of Bone Marrow Derived Mesenchymal Stem Cells on Hair Follicle Regeneration
Bone marrow stem cells and their medium help hair regrowth.
research Desmoplastic Tricholemmoma in a Dog
A dog had a rare skin tumor called desmoplastic tricholemmoma.
research Obesity and Wound Healing: Focus on Mesenchymal Stem Cells
Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
research DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Chromatin Topology in Lineage-Specific Loci to Control Epithelial Differentiation
The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
research Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules
Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
research Non-Histone Methylation of SET7/9 and Its Biological Functions
SET7/9 enzyme affects cell growth and diseases like cancer, diabetes, and obesity.
research Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature
Scalp melanoma, a deadly skin cancer, is often found late due to its hard-to-see location, especially in older men. Early detection, possible treatments, and the role of hairdressers in spotting it early are discussed. More research is needed to improve detection and treatment.
research Usefulness of Dermoscopy to Provide Accurate Assessment of Skin Cancers
Dermoscopy is an effective tool for accurately detecting skin cancers.
research Expansion of Specialized Epidermis Induced by Hormonal State and Mechanical Strain
Hormones and stretching both needed for nipple area skin growth in mice.
research Exploiting the Origins of Ras-Mediated Squamous Cell Carcinoma to Develop Novel Therapeutic Interventions
Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.
research Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions
Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
research Hair Lipid Structure: Effect of Surfactants
Surfactants in shampoos and conditioners remove some but not all lipids from hair, and more research is needed to understand their full impact.