1 citations
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October 2021 in “QJM: An International Journal of Medicine” This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.
1 citations
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January 2017 in “Indian Dermatology Online Journal” This commentary reviews clinical trials on platelet-rich plasma treatments for androgenetic alopecia and emphasizes the need for standardized preparation methods and concentrations; it reports no new clinical results.
October 2025 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” This study found that both single spin and double spin techniques of PRP preparation significantly improved hair growth in male androgenetic alopecia, with no statistical difference between the methods.
July 2025 in “Frontiers in Medicine” In this systematic review and meta-analysis, the authors examined single-spin versus double-spin centrifugation protocols for PRP in patients with androgenic alopecia and found no significant difference in platelet concentration, hair density, or hair types between the protocols.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found no significant differences in platelet concentration or hair growth outcomes between single-spin and double-spin PRP centrifugation methods for treating androgenic alopecia, suggesting that the simpler single-spin approach may be preferable.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this systematic review and meta-analysis, the researchers found no significant difference in platelet concentration, hair density improvement, or changes in terminal and vellus hair rates between single-spin and double-spin PRP centrifugation protocols in treating androgenic alopecia.
January 2025 in “Journal of Bacha Khan Medical College.” This study compared two PRP preparation techniques for treating androgenetic alopecia and found that both methods led to some improvement in hair loss, but further research is suggested due to variations in PRP preparation.
January 1997 in “Purdue e-Pubs (Purdue University)” This study suggested that electron spin resonance techniques can potentially measure gamma ray exposure in human hair samples, though variability and time sensitivity pose challenges for accurate dose estimation.
December 2023 in “PubMed” This study found that both single- and double-spin PRP preparation methods significantly increased thrombocyte counts and improved hair parameters in males with androgenetic alopecia, with the single-spin method showing a more significant increase in thrombocyte count.
27 citations
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January 2017 in “Indian Dermatology Online Journal” This study found no significant benefit from PRP injections for treating androgenetic alopecia in men, highlighting the need for larger, well-designed trials to assess its effectiveness and safety.
November 2025 in “Eduvest - Journal Of Universal Studies” This case report describes a young male patient with androgenetic alopecia who experienced significant hair growth improvement and no side effects after receiving single spin platelet-rich plasma therapy combined with topical minoxidil.
June 2021 in “Current Biochemistry” This study determined that a 6.25% concentration of propolis effectively inhibits the growth of dandruff-causing bacteria, with effectiveness values of 223.52% and 99.59% compared to ketoconazole and another propolis extract, respectively.
2 citations
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May 2024 in “Cureus” This study found that both single and double spin platelet-rich plasma methods significantly reduced chronic ulcer surface area, with single spin showing notable healing improvements.
1 citations
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June 2023 in “Journal of applied crystallography” This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.
January 2020 in “Platelet Rich Plasma in Androgenetic Alopecia- A Prospective Study.” January 2022 in “JURNAL BIOSAINS” This study found that a hair tonic made with 10% cassava leaf extract in combination with rose water juice improved hair length growth in rabbits compared to a commercial product.
5 citations
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April 2016 in “Proceedings of the Latvian Academy of Sciences. Section B, Natural, Exact and Applied Sciences” This study fabricated a polyamide fiber containing amber particles and characterized its potential for textile applications, noting that the chemical structure of amber remained unchanged after grinding and integration.
December 2023 in “Journal of molecular structure” This study found that hair membrane fluidity is low in the cuticle but high in the cortex and medulla, with treatments like ionic surfactants and oleic acid increasing fluidity in hydrated hair; however, dehydration significantly reduces fluidity throughout the hair.
125 citations
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September 2001 in “The FASEB Journal” This study demonstrated that stress inhibited hair growth in mice, likely through substance P-dependent activation of immune cells, highlighting a brain-hair follicle connection.
112 citations
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February 2001 in “Journal of Investigative Dermatology” This study found that substance P and calcitonin-gene-related peptide have different roles in regulating hair growth in mice, with substance P promoting anagen progression and calcitonin-gene-related peptide inhibiting it.
76 citations
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April 2013 in “PLoS ONE” The researchers reported that reactive oxygen species regulate the stress-induced SP-Mast cell pathway, which might support using antioxidants to treat stress-related hair loss.
66 citations
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July 2007 in “Journal of Molecular Medicine” This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.
8 citations
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January 2020 in “Skin appendage disorders” This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.
3 citations
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July 2023 in “International journal of molecular sciences” This review discusses the association between emotional stress-related neuropeptides and the pathogenesis of alopecia areata, reporting no new experimental findings.
3 citations
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August 2018 in “Deleted Journal” This study found that Guasha therapy did not significantly alter nerve fiber morphology or the expression of CGRP and SP in rat skin, with parameters generally returning to normal within five days.
3 citations
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April 2012 in “Cancer research” This study reports that side-population stem cells, distinct from hair follicle stem cells, may play a significant role in the malignant progression of squamous cell carcinomas in mice.
January 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that patients with trichodynia associated with androgenetic alopecia had significantly higher levels of substance P in both tissue and serum compared to healthy controls, suggesting a potential role for this neurotransmitter in the condition's pathogenesis.
December 2024 in “Pharmaceutics” This review systematically examined recent advancements in spironolactone-loaded nanocarriers, revealing that lipid and vesicular nanoparticles enhance bioavailability and skin penetration for treating androgen-dependent disorders, but highlighted the need for further clinical studies to optimize their use.
21 citations
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July 2015 in “International Journal of Nanomedicine” In this study, ultradeformable liposomes containing Tween 20 or terpenes increased phospholipid bilayer fluidity and enhanced skin penetration of sodium fluorescein, with terpenes improving hair follicle penetration.
10 citations
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August 2020 in “Dermatologic Therapy” This study found that platelet-rich plasma significantly increased hair diameter in both men and women with androgenetic alopecia but improved hair density only in men.