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The testes produce sperm and hormones essential for male development.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Stopping finasteride can improve sperm count in infertile men.

Finasteride does not negatively affect male reproductive function.

Men with lower education levels are more likely to have erectile dysfunction if they have coronary artery disease.

The document covers various male health issues, their causes, treatments, and related conditions.

Finasteride helps female-pattern hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.