research Androgen Receptor: A Promising Therapeutic Target in Breast Cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
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research Elicitor Mediated Enhancement of Wedelolactone in Cell Suspension Culture of Eclipta Alba (L.) Hassk
Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.
research Male Androgenetic Alopecia
Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
research Dermatologic Adverse Events in Pediatric Patients Receiving Targeted Anticancer Therapies: A Pooled Analysis
Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.
research Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force Dermatology for Cancer Patients International Study
Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Testosterone Therapy for Transgender Men: Effects and Safety
Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
research Sexual Dysfunction Related to Drugs: A Critical Review. Part V: Alpha-Blocker and 5-ARI Drugs
α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.
research Industry News
The U.S. soybean industry wanted government help due to foreign competition, while the jojoba industry was growing and expected to stabilize.
research Diagnostic Criteria for Enduring Sexual Dysfunction After Treatment With Antidepressants, Finasteride, and Isotretinoin
The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
research Formulation and Evaluation of Clove Leaf Ethanol Extract Shampoo (Syzygium Aromaticum L) as Hair Growth Promoter in Male White Rats
A 15% clove leaf extract shampoo promotes hair growth but is less effective than minoxidil.
research Spigo Nardo: From the Este Herbarium a Possible Solution for Its Taxonomical Attribution
Researchers concluded that "spigo nardo" is the Himalayan plant Nardostachys jatamansi, used historically in medicine and cosmetics, now critically endangered.
research Finasteride-Induced Secondary Infertility Associated with Sperm DNA Damage
Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Sperm Aneuploidy in Infertile Male Patients: A Systematic Review of the Literature
Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.
research Origanum Vulgare L. Leaves Extract Alleviates Testis And Sperm Damages Induced By Finasteride: Biochemical, Immunohistological And Apoptosis Genes Based Evidences
Oregano extract helps fix testis and sperm damage caused by finasteride.
research Finasteride Interferes with Prostaglandin-Induced CatSper Signalling in Human Sperm
Finasteride may affect male fertility by interfering with specific sperm signaling.
research Subchronic Study of Sperm Morphology, Genotoxic and Mutagenic Effect of Lepidium Sativum Seeds Aqueous Extract In Vivo
High doses of Lepidium sativum seed extract are toxic and should be used with caution.
research Effect of Testosterone, Dihydrotestosterone, Estradiol, and Cortisol on the Quality of Fresh and Cryopreserved Stallion Sperm
Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.
research 5-Aminolevulinic Acid Improves Chicken Sperm Motility
5-Aminolevulinic acid can help chicken sperm move better at the right amount.
research Finasteride and Sperm Concentration: Rapid Systematic Review
Finasteride appears safe for long-term sperm concentration, but more research is needed for clear conclusions.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research The Voices of Adult Offspring of Sperm Donation: Forces for Change Within Assisted Reproductive Technology in the United States
Adult offspring of sperm donation generally feel positive about their conception and view the donor as their biological father.
research Impact of Microbial Infection on Sperm Parameters of Seminal Bacteria in Asymptomatic Subfertile Males
Seminal bacteria can lower sperm quality in subfertile men.
research The First Visit: Consultation and Workup Before Sperm Banking
A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.
research Recent Advances in Understanding and Managing Male Infertility
Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.
research Finasteride Use in the Male Infertility Population: Effects on Semen and Hormone Parameters
Finasteride can reduce fertility in some men, but stopping it increases sperm count.
research Finasteride-Associated Male Infertility
Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
research Is Age at Puberty Associated with Semen Quality and Reproductive Hormones in Young Adult Life?
Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.
research 5α-Reductase Inhibitors and Male Reproduction
5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.