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Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.

Polyamines help fix DNA damage accurately in cells.

Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.

Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.

Stopping finasteride can improve sperm count in infertile men.

Finasteride discontinuation increases sperm count in men.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Cynomorium songaricum has many health benefits and could help with hair regrowth.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.