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Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

High doses of Lepidium sativum seed extract are toxic and should be used with caution.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Finasteride doesn't change rat testicle weight or sperm production.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Some nonsurgical hair loss treatments are effective, especially if started early.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

Stem cells can help other stem cells by producing supportive factors.

GPRC5D is linked to the formation of hair, nails, and certain tongue areas.

More research is needed to understand how testosterone is maintained in adult males.

Zinc is essential for many body functions and imbalances can lead to health problems.

The document explains how male reproductive hormones work and affect the body.