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Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.

Stem cell niches support, regulate, and coordinate stem cell functions.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

Quaternary ammonium iminofullerenes help maize roots grow better under stress by reducing oxidative damage.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Most Sudanese married women in the study used contraceptives and knew about them, but many didn't know about emergency contraceptives or extra benefits beyond family planning.

Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.

CDP is crucial for lung and hair follicle cell development.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.

Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Onions may help reduce cancer risk and obesity-related issues.

Two teenage boys lost hair after taking a drug for growth, which was not a known side effect for kids.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Saw palmetto can help with prostate issues and may promote hair growth.

PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.